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Role of Sostdc1 in skeletal biology and cancer

Sclerostin domain-containing protein-1 (Sostdc1) is a member of the sclerostin family and encodes a secreted 28–32 kDa protein with a cystine knot-like domain and two N-linked glycosylation sites. Sostdc1 functions as an antagonist to bone morphogenetic protein (BMP), mediating BMP signaling. It als...

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Detalles Bibliográficos
Autores principales: Tong, Xiaoyang, Zhu, Chenyu, Liu, Lifei, Huang, Mei, Xu, Jiake, Chen, Xi, Zou, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633957/
https://www.ncbi.nlm.nih.gov/pubmed/36338475
http://dx.doi.org/10.3389/fphys.2022.1029646