Heart Failure and Diabetes Mellitus: Dangerous Liaisons

Patients with diabetes mellitus (DM) have a higher prevalence of heart failure (HF) than those without it. Approximately 40% of HF patients have DM, having poorer outcomes than those without DM. Myocardial ischemia caused by endothelial dysfunction, renal dysfunction, obesity, and impaired myocardia...

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Detalles Bibliográficos
Autor principal: Lee, Hae-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Heart Failure 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634025/
https://www.ncbi.nlm.nih.gov/pubmed/36381018
http://dx.doi.org/10.36628/ijhf.2022.0022
Descripción
Sumario:Patients with diabetes mellitus (DM) have a higher prevalence of heart failure (HF) than those without it. Approximately 40% of HF patients have DM, having poorer outcomes than those without DM. Myocardial ischemia caused by endothelial dysfunction, renal dysfunction, obesity, and impaired myocardial energetics is pathophysiology of DM-induced HF (DM-HF). Also, patients with HF show an increased risk for the onset of DM due to several mechanisms including insulin resistance. This review is focused on the epidemiology, pathogenic mechanism and treatment strategy of DM-HF.

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