Cargando…

MMPP promotes adipogenesis and glucose uptake via binding to the PPARγ ligand binding domain in 3T3-L1 MBX cells

Peroxisome proliferator-activated receptor-gamma (PPARγ) is a transcription factor involved in adipogenesis, and its transcriptional activity depends on its ligands. Thiazolidinediones (TZDs), well-known PPARγ agonists, are drugs that improve insulin resistance in type 2 diabetes. However, TZDs are...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Na-Yeon, Lim, Chae-Min, Park, Hyo-Min, Kim, Jinju, Pham, Thu-Huyen, Yang, Young, Lee, Hee Pom, Hong, Jin Tae, Yoon, Do-Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634037/ https://www.ncbi.nlm.nih.gov/pubmed/36339572 http://dx.doi.org/10.3389/fphar.2022.994584

Ejemplares similares

MMPP Exerts Anti-Inflammatory Effects by Suppressing MD2-Dependent NF-κB and JNK/AP-1 Pathways in THP-1 Monocytes
por: Kim, Seonhwa, et al.
Publicado: (2023)

MMPP Attenuates Non-Small Cell Lung Cancer Growth by Inhibiting the STAT3 DNA-Binding Activity via Direct Binding to the STAT3 DNA-Binding Domain
por: Son, Dong Ju, et al.
Publicado: (2017)

Cross-Species Differential Plasma Protein Binding of MBX-102/JNJ39659100: A Novel PPAR-γ Agonist
por: Clarke, Holly J., et al.
Publicado: (2008)

MBX-102/JNJ39659100, a Novel Non-TZD Selective Partial PPAR-γ Agonist Lowers Triglyceride Independently of PPAR-α Activation
por: Chandalia, Apurva, et al.
Publicado: (2009)

Phenolic Compounds Inhibit 3T3-L1 Adipogenesis Depending on the Stage of Differentiation and Their Binding Affinity to PPARγ
por: Aranaz, Paula, et al.
Publicado: (2019)

Ligand Binding and Activation of PPARγ by Firemaster(®) 550: Effects on Adipogenesis and Osteogenesis in Vitro
por: Pillai, Hari K., et al.
Publicado: (2014)

Osterix represses adipogenesis by negatively regulating PPARγ transcriptional activity
por: Han, Younho, et al.
Publicado: (2016)

STAT3 and p53: Dual Target for Cancer Therapy
por: Pham, Thu-Huyen, et al.
Publicado: (2020)

Prostaglandins as PPARγ Modulators in Adipogenesis
por: Fujimori, Ko
Publicado: (2012)

De-Novo Identification of PPARγ/RXR Binding Sites and Direct Targets during Adipogenesis
por: Hamza, Mohamed Sabry, et al.
Publicado: (2009)

Histone H3K9 Demethylase JMJD2B Activates Adipogenesis by Regulating H3K9 Methylation on PPARγ and C/EBPα during Adipogenesis
por: Jang, Min-Kyung, et al.
Publicado: (2017)

Timcodar (VX-853) Is a Non-FKBP12 Binding Macrolide Derivative That Inhibits PPARγ and Suppresses Adipogenesis
por: Hinds, Terry D., et al.
Publicado: (2016)

Derhamnosylmaysin Inhibits Adipogenesis via Inhibiting Expression of PPARγ and C/EBPα in 3T3-L1 Cells
por: Cho, Hang-Hee, et al.
Publicado: (2022)

Apigetrin inhibits adipogenesis in 3T3-L1 cells by downregulating PPARγ and CEBP-α
por: Hadrich, Fatma, et al.
Publicado: (2018)

Interleukin-32θ Triggers Cellular Senescence and Reduces Sensitivity to Doxorubicin-Mediated Cytotoxicity in MDA-MB-231 Cells
por: Pham, Thu-Huyen, et al.
Publicado: (2021)

Transcriptional and epigenetic regulation of PPARγ expression during adipogenesis
por: Lee, Ji-Eun, et al.
Publicado: (2014)

CACUL1 reciprocally regulates SIRT1 and LSD1 to repress PPARγ and inhibit adipogenesis
por: Jang, Min Jun, et al.
Publicado: (2017)

An alternate binding site for PPARγ ligands
por: Hughes, Travis S., et al.
Publicado: (2014)

Gsα signalling suppresses PPARγ2 generation and inhibits 3T3L1 adipogenesis
por: Zhang, Lei, et al.
Publicado: (2009)

Ups and downs: The PPARγ/p-PPARγ seesaw of follistatin-like 1 and integrin receptor signaling in adipogenesis
por: Fang, Dongliang, et al.
Publicado: (2021)

STK38 is a PPARγ-interacting protein promoting adipogenesis
por: Qian, Kun, et al.
Publicado: (2021)

Betulinic acid is a PPARγ antagonist that improves glucose uptake, promotes osteogenesis and inhibits adipogenesis
por: Brusotti, Gloria, et al.
Publicado: (2017)

T-Cell Death-Associated Gene 51 Is a Novel Negative Regulator of PPARγ That Inhibits PPARγ-RXRα Heterodimer Formation in Adipogenesis
por: Kim, Sumi, et al.
Publicado: (2021)

Nuclear Receptor Cofactors in PPARγ-Mediated Adipogenesis and Adipocyte Energy Metabolism
por: Powell, Emily, et al.
Publicado: (2007)

Rock signaling control PPARγ expression and actin polymerization during adipogenesis
por: Ji, Yuntao, et al.
Publicado: (2017)

Characterizing 3T3-L1 MBX Adipocyte Cell Differentiation Maintained with Fatty Acids as an In Vitro Model to Study the Effects of Obesity
por: Mubtasim, Noshin, et al.
Publicado: (2023)

Structural investigation of ginsenoside Rf with PPARγ major transcriptional factor of adipogenesis and its impact on adipocyte
por: Siraj, Fayeza Md, et al.
Publicado: (2015)

A proline-type fullerene derivative inhibits adipogenesis by preventing PPARγ activation
por: Funakoshi-Tago, Megumi, et al.
Publicado: (2016)

Erratum: “The Role of Dietary Phytoestrogens and the Nuclear Receptor PPARγ in Adipogenesis: An in Vitro Study”
por: Hall, Julie M., et al.
Publicado: (2019)

MiR-19 Family Impairs Adipogenesis by the Downregulation of the PPARγ Transcriptional Network
por: Juiz-Valiña, Paula, et al.
Publicado: (2022)

Microfibrillar-associated protein 5 suppresses adipogenesis by inhibiting essential coactivator of PPARγ
por: Zhang, Tianlong, et al.
Publicado: (2023)

GATA binding protein 3 is correlated with leptin regulation of PPARγ1 in hepatic stellate cells
por: Guan, Wei, et al.
Publicado: (2016)

A dietary anthocyanin cyanidin-3-O-glucoside binds to PPARs to regulate glucose metabolism and insulin sensitivity in mice
por: Jia, Yaoyao, et al.
Publicado: (2020)

Nonivamide Enhances miRNA let‐7d Expression and Decreases Adipogenesis PPARγ Expression in 3T3‐L1 Cells
por: Rohm, Barbara, et al.
Publicado: (2015)

The Role of PPARγ in Helicobacter pylori Infection and Gastric Carcinogenesis
por: Lee, Jong-Min, et al.
Publicado: (2012)

Regulation of adipogenesis by nuclear receptor PPARγ is modulated by the histone demethylase JMJD2C
por: Lizcano, Fernando, et al.
Publicado: (2011)

Coordinated Regulation of PPARγ Expression and Activity through Control of Chromatin Structure in Adipogenesis and Obesity
por: Eeckhoute, Jérôme, et al.
Publicado: (2012)

TonEBP suppresses adipogenesis and insulin sensitivity by blocking epigenetic transition of PPARγ2
por: Ho Lee, Jun, et al.
Publicado: (2015)

Identification of a novel selective agonist of PPARγ with no promotion of adipogenesis and less inhibition of osteoblastogenesis
por: Liu, Chang, et al.
Publicado: (2015)

PPARγ Controls Ectopic Adipogenesis and Cross-Talks with Myogenesis During Skeletal Muscle Regeneration
por: Dammone, Gabriele, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_rgo1s2iumourvm0t1nh9knj8gn