Cargando…

1,3-Dibenzyl-5-Fluorouracil Prevents Ovariectomy-Induced Bone Loss by Suppressing Osteoclast Differentiation

Osteoclasts (OCs) are clinically important cells that resorb bone matrix. Accelerated bone destruction by OCs is closely linked to the development of metabolic bone diseases. In this study, we screened novel chemical inhibitors targeting OC differentiation to identify drug candidates for metabolic b...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jeon, Hyoeun, Yu, Jungeun, Hwang, Jung Me, Park, Hye-Won, Yu, Jiyeon, Lee, Zee-Won, Kim, Taesoo, Rho, Jaerang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Association of Immunologists 2022
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634144/ https://www.ncbi.nlm.nih.gov/pubmed/36381956 http://dx.doi.org/10.4110/in.2022.22.e43

Ejemplares similares

TDAG51 deficiency attenuates dextran sulfate sodium-induced colitis in mice
por: Jeon, Hyoeun, et al.
Publicado: (2022)

Pax5 Negatively Regulates Osteoclastogenesis through Downregulation of Blimp1
por: Yu, Jiyeon, et al.
Publicado: (2021)

Amaranthus mangostanus Inhibits the Differentiation of Osteoclasts and Prevents Ovariectomy-Induced Bone Loss
por: Jeong, Yeon-Hui, et al.
Publicado: (2020)

Bone Loss Triggered by the Cytokine Network in Inflammatory Autoimmune Diseases
por: Amarasekara, Dulshara Sachini, et al.
Publicado: (2015)

T-Cell Death-Associated Gene 51 Is a Novel Negative Regulator of PPARγ That Inhibits PPARγ-RXRα Heterodimer Formation in Adipogenesis
por: Kim, Sumi, et al.
Publicado: (2021)

Regulation of Osteoclast Differentiation by Cytokine Networks
por: Amarasekara, Dulshara Sachini, et al.
Publicado: (2018)

Water Extract of Piper longum Linn Ameliorates Ovariectomy-Induced Bone Loss by Inhibiting Osteoclast Differentiation
por: Gu, Dong Ryun, et al.
Publicado: (2022)

Soluble RANKL contributes to osteoclast formation in adult mice but not ovariectomy-induced bone loss
por: Xiong, Jinhu, et al.
Publicado: (2018)

Oroxin B Attenuates Ovariectomy-Induced Bone Loss by Suppressing Osteoclast Formation and Activity
por: Huang, Jun-ming, et al.
Publicado: (2021)

A Novel Member of the Leukocyte Receptor Complex Regulates Osteoclast Differentiation
por: Kim, Nacksung, et al.
Publicado: (2002)

Rutin Improves Bone Histomorphometric Values by Reduction of Osteoclastic Activity in Osteoporosis Mouse Model Induced by Bilateral Ovariectomy
por: Lee, Hye-Hwa, et al.
Publicado: (2020)

Protective Effect of Ciclopirox against Ovariectomy-Induced Bone Loss in Mice by Suppressing Osteoclast Formation and Function
por: Ihn, Hye Jung, et al.
Publicado: (2021)

Water Extract of Agastache rugosa Prevents Ovariectomy-Induced Bone Loss by Inhibiting Osteoclastogenesis
por: Jang, Seon-A, et al.
Publicado: (2020)

Pristimerin Inhibits Osteoclast Differentiation and Bone Resorption in vitro and Prevents Ovariectomy-Induced Bone Loss in vivo
por: Sun, Peng, et al.
Publicado: (2020)

1,3-Dibenzylimidazolidine-2-thione
por: Mietlarek-Kropidłowska, Anna, et al.
Publicado: (2012)

Hwangryun-Haedok-Tang Fermented with Lactobacillus casei Suppresses Ovariectomy-Induced Bone Loss
por: Shim, Ki-Shuk, et al.
Publicado: (2012)

Selective Regulation of MAPK Signaling Mediates RANKL-dependent Osteoclast Differentiation
por: Lee, Kyunghee, et al.
Publicado: (2016)

Phillyrin Prevents Ovariectomy-Induced Osteolysis by Inhibiting Osteoclast Differentiation
por: Zhang, Geng, et al.
Publicado: (2022)

Ethanol Extract of Amomum tsao-ko Ameliorates Ovariectomy-Induced Trabecular Loss and Fat Accumulation
por: Shim, Ki-Shuk, et al.
Publicado: (2021)

1,3-Dibenzyl-2-methylbenzimidazolium chloride
por: Ennajih, Hamid, et al.
Publicado: (2010)

Sphingosylphosphorylcholine blocks ovariectomy‐induced bone loss by suppressing Ca(2+)/calmodulin‐mediated osteoclast differentiation
por: Lee, Ha Young, et al.
Publicado: (2020)

Lactobacillus fermentation enhances the inhibitory effect of Hwangryun-haedok-tang in an ovariectomy-induced bone loss
por: Shim, Ki-Shuk, et al.
Publicado: (2013)

Dibenzyl sulfoxide
por: Zeng, Yun-Xiu, et al.
Publicado: (2010)

Engineered Recombinant PON1-OPH Fusion Hybrids: Potentially Effective Catalytic Bioscavengers against Organophosphorus Nerve Agent Analogs
por: Lee, Nari, et al.
Publicado: (2021)

Isosteviol Derivative Inhibits Osteoclast Differentiation and Ameliorates Ovariectomy-Induced Osteoporosis
por: Tzeng, Huey-En, et al.
Publicado: (2018)

Isovaleric acid ameliorates ovariectomy‐induced osteoporosis by inhibiting osteoclast differentiation
por: Cho, Kwang Min, et al.
Publicado: (2021)

(−)-Epiafzelechin Protects against Ovariectomy-induced Bone Loss in Adult Mice and Modulate Osteoblastic and Osteoclastic Functions In Vitro
por: Wong, Ka-Chun, et al.
Publicado: (2017)

Rhus javanica Gall Extract Inhibits the Differentiation of Bone Marrow-Derived Osteoclasts and Ovariectomy-Induced Bone Loss
por: Kim, Tae-Ho, et al.
Publicado: (2016)

N,N-Dibenzylmethanesulfonamide
por: Datta, Mrityunjoy, et al.
Publicado: (2008)

Artemisia annua extract prevents ovariectomy-induced bone loss by blocking receptor activator of nuclear factor kappa-B ligand-induced differentiation of osteoclasts
por: Lee, Sun Kyoung, et al.
Publicado: (2017)

Phlpp1 is induced by estrogen in osteoclasts and its loss in Ctsk-expressing cells does not protect against ovariectomy-induced bone loss
por: Hanson, Marcelline K., et al.
Publicado: (2021)

Dibenzyldichloridotin(IV)
por: Lo, Kong Mun, et al.
Publicado: (2009)

Pregnenolone Inhibits Osteoclast Differentiation and Protects Against Lipopolysaccharide-Induced Inflammatory Bone Destruction and Ovariectomy-Induced Bone Loss
por: Sun, Xiaochen, et al.
Publicado: (2020)

Acacetin Prevents Bone Loss by Disrupting Osteoclast Formation and Promoting Type H Vessel Formation in Ovariectomy-Induced Osteoporosis
por: Lin, Xiao, et al.
Publicado: (2022)

Isoliensinine Suppresses Osteoclast Formation Through NF-κB Signaling Pathways and Relieves Ovariectomy-Induced Bone Loss
por: Liu, Huijiang, et al.
Publicado: (2022)

Vibrational Spectra and Molecular Vibrational Behaviors of Dibenzyl Disulfide, Dibenzyl Sulphide and Bibenzyl
por: Wang, Ziyi, et al.
Publicado: (2022)

2-(1,3-Dibenzylimidazolidin-2-ylidene)malononitrile
por: Feng, Xiao-Zhong, et al.
Publicado: (2008)

Selenoprotein W ensures physiological bone remodeling by preventing hyperactivity of osteoclasts
por: Kim, Hyunsoo, et al.
Publicado: (2021)

Nicorandil Inhibits Osteoclast Formation Base on NF-κB and p-38 MAPK Signaling Pathways and Relieves Ovariectomy-Induced Bone Loss
por: Xu, Shenggui, et al.
Publicado: (2021)

Fermented Oyster Extract Prevents Ovariectomy-Induced Bone Loss and Suppresses Osteoclastogenesis
por: Ihn, Hye Jung, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_c2q67sk7164qpnaib2d1s2mt9f