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IκBNS expression in B cells is dispensable for IgG responses to T cell-dependent antigens

Mice lacking the atypical inhibitory kappa B (IκB) protein, IκBNS, a regulator of the NF-κB pathway encoded by the nfkbid gene, display impaired antibody responses to both T cell-independent (TI) and T cell-dependent (TD) antigens. To better understand the basis of these defects, we crossed mice car...

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Detalles Bibliográficos
Autores principales: Khoenkhoen, Sharesta, Ádori, Monika, Solís-Sayago, Darío, Soulier, Juliette, Russell, Jamie, Beutler, Bruce, Pedersen, Gabriel K., Karlsson Hedestam, Gunilla B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634154/
https://www.ncbi.nlm.nih.gov/pubmed/36341341
http://dx.doi.org/10.3389/fimmu.2022.1000755