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IκBNS expression in B cells is dispensable for IgG responses to T cell-dependent antigens
Mice lacking the atypical inhibitory kappa B (IκB) protein, IκBNS, a regulator of the NF-κB pathway encoded by the nfkbid gene, display impaired antibody responses to both T cell-independent (TI) and T cell-dependent (TD) antigens. To better understand the basis of these defects, we crossed mice car...
Autores principales: | Khoenkhoen, Sharesta, Ádori, Monika, Solís-Sayago, Darío, Soulier, Juliette, Russell, Jamie, Beutler, Bruce, Pedersen, Gabriel K., Karlsson Hedestam, Gunilla B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634154/ https://www.ncbi.nlm.nih.gov/pubmed/36341341 http://dx.doi.org/10.3389/fimmu.2022.1000755 |
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