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Multi-spectral immunofluorescence evaluation of the myeloid, T cell, and natural killer cell tumor immune microenvironment in chordoma may guide immunotherapeutic strategies

BACKGROUND: Chordoma is a rare, invasive, and devastating bone malignancy of residual notochord tissue that arises at the skull base, sacrum, or spine. In order to maximize immunotherapeutic approaches as a potential treatment strategy in chordoma it is important to fully characterize the tumor immu...

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Detalles Bibliográficos
Autores principales: Lopez, Diana C., Robbins, Yvette L., Kowalczyk, Joshua T., Lassoued, Wiem, Gulley, James L., Miettinen, Markku M., Gallia, Gary L., Allen, Clint T., Hodge, James W., London, Nyall R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634172/
https://www.ncbi.nlm.nih.gov/pubmed/36338744
http://dx.doi.org/10.3389/fonc.2022.1012058