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Multi-spectral immunofluorescence evaluation of the myeloid, T cell, and natural killer cell tumor immune microenvironment in chordoma may guide immunotherapeutic strategies
BACKGROUND: Chordoma is a rare, invasive, and devastating bone malignancy of residual notochord tissue that arises at the skull base, sacrum, or spine. In order to maximize immunotherapeutic approaches as a potential treatment strategy in chordoma it is important to fully characterize the tumor immu...
Autores principales: | Lopez, Diana C., Robbins, Yvette L., Kowalczyk, Joshua T., Lassoued, Wiem, Gulley, James L., Miettinen, Markku M., Gallia, Gary L., Allen, Clint T., Hodge, James W., London, Nyall R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634172/ https://www.ncbi.nlm.nih.gov/pubmed/36338744 http://dx.doi.org/10.3389/fonc.2022.1012058 |
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