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Effects of tannic acid on growth performance, relative organ weight, antioxidative status, and intestinal histomorphology in broilers exposed to aflatoxin B(1)
A total of 480 one-day-old AA broiler chicks were randomly allocated to one of four treatments in a 2 × 2 factorial to investigate the effects of tannic acid (TA) on growth performance, relative organ weight, antioxidant capacity, and intestinal health in broilers dietary exposed to aflatoxin B(1) (...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634217/ https://www.ncbi.nlm.nih.gov/pubmed/36337182 http://dx.doi.org/10.3389/fvets.2022.1037046 |
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author | Xi, Yu Chen, Jing Guo, Shuangshuang Wang, Sitian Liu, Zhipeng Zheng, Liyun Qi, Ya Xu, Pengtao Li, Lanlan Zhang, Zhengfan Ding, Binying |
author_facet | Xi, Yu Chen, Jing Guo, Shuangshuang Wang, Sitian Liu, Zhipeng Zheng, Liyun Qi, Ya Xu, Pengtao Li, Lanlan Zhang, Zhengfan Ding, Binying |
author_sort | Xi, Yu |
collection | PubMed |
description | A total of 480 one-day-old AA broiler chicks were randomly allocated to one of four treatments in a 2 × 2 factorial to investigate the effects of tannic acid (TA) on growth performance, relative organ weight, antioxidant capacity, and intestinal health in broilers dietary exposed to aflatoxin B(1) (AFB(1)). Treatments were as follows: (1) CON, control diet; (2) TA, CON + 250 mg/kg TA; (3) AFB(1), CON + 500 μg/kg AFB(1); and (4) TA+AFB(1), CON + 250 mg/kg TA + 500 μg/kg AFB(1). There were 10 replicate pens with 12 broilers per replicate. Dietary AFB(1) challenge increased the feed conversion ratio during days 1 to 21 (P < 0.05). The TA in the diet did not show significant effects on the growth performance of broilers during the whole experiment period (P > 0.05). The liver and kidney relative weight was increased in the AF challenge groups compared with the CON (P < 0.05). The addition of TA could alleviate the relative weight increase of liver and kidney caused by AFB(1) (P < 0.05). Broilers fed the AFB(1) diets had lower activity of glutathione peroxidase, catalase, total superoxide dismutase, S-transferase, and total antioxidant capacity in plasma, liver and jejunum, and greater malondialdehyde content (P < 0.05). Dietary supplemented with 250 mg/kg TA increased the activities of antioxidative enzymes, and decreased malondialdehyde content (P < 0.05). In addition, AFB(1) significantly reduced the villus height and crypt depth ratio in the ileum on day 42 (P < 0.05). In conclusion, supplementation with 250 mg/kg TA could partially protect the antioxidant capacity and prevent the enlargement of liver in broilers dietary challenged with 500 μg/kg AFB(1). |
format | Online Article Text |
id | pubmed-9634217 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-96342172022-11-05 Effects of tannic acid on growth performance, relative organ weight, antioxidative status, and intestinal histomorphology in broilers exposed to aflatoxin B(1) Xi, Yu Chen, Jing Guo, Shuangshuang Wang, Sitian Liu, Zhipeng Zheng, Liyun Qi, Ya Xu, Pengtao Li, Lanlan Zhang, Zhengfan Ding, Binying Front Vet Sci Veterinary Science A total of 480 one-day-old AA broiler chicks were randomly allocated to one of four treatments in a 2 × 2 factorial to investigate the effects of tannic acid (TA) on growth performance, relative organ weight, antioxidant capacity, and intestinal health in broilers dietary exposed to aflatoxin B(1) (AFB(1)). Treatments were as follows: (1) CON, control diet; (2) TA, CON + 250 mg/kg TA; (3) AFB(1), CON + 500 μg/kg AFB(1); and (4) TA+AFB(1), CON + 250 mg/kg TA + 500 μg/kg AFB(1). There were 10 replicate pens with 12 broilers per replicate. Dietary AFB(1) challenge increased the feed conversion ratio during days 1 to 21 (P < 0.05). The TA in the diet did not show significant effects on the growth performance of broilers during the whole experiment period (P > 0.05). The liver and kidney relative weight was increased in the AF challenge groups compared with the CON (P < 0.05). The addition of TA could alleviate the relative weight increase of liver and kidney caused by AFB(1) (P < 0.05). Broilers fed the AFB(1) diets had lower activity of glutathione peroxidase, catalase, total superoxide dismutase, S-transferase, and total antioxidant capacity in plasma, liver and jejunum, and greater malondialdehyde content (P < 0.05). Dietary supplemented with 250 mg/kg TA increased the activities of antioxidative enzymes, and decreased malondialdehyde content (P < 0.05). In addition, AFB(1) significantly reduced the villus height and crypt depth ratio in the ileum on day 42 (P < 0.05). In conclusion, supplementation with 250 mg/kg TA could partially protect the antioxidant capacity and prevent the enlargement of liver in broilers dietary challenged with 500 μg/kg AFB(1). Frontiers Media S.A. 2022-10-21 /pmc/articles/PMC9634217/ /pubmed/36337182 http://dx.doi.org/10.3389/fvets.2022.1037046 Text en Copyright © 2022 Xi, Chen, Guo, Wang, Liu, Zheng, Qi, Xu, Li, Zhang and Ding. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Veterinary Science Xi, Yu Chen, Jing Guo, Shuangshuang Wang, Sitian Liu, Zhipeng Zheng, Liyun Qi, Ya Xu, Pengtao Li, Lanlan Zhang, Zhengfan Ding, Binying Effects of tannic acid on growth performance, relative organ weight, antioxidative status, and intestinal histomorphology in broilers exposed to aflatoxin B(1) |
title | Effects of tannic acid on growth performance, relative organ weight, antioxidative status, and intestinal histomorphology in broilers exposed to aflatoxin B(1) |
title_full | Effects of tannic acid on growth performance, relative organ weight, antioxidative status, and intestinal histomorphology in broilers exposed to aflatoxin B(1) |
title_fullStr | Effects of tannic acid on growth performance, relative organ weight, antioxidative status, and intestinal histomorphology in broilers exposed to aflatoxin B(1) |
title_full_unstemmed | Effects of tannic acid on growth performance, relative organ weight, antioxidative status, and intestinal histomorphology in broilers exposed to aflatoxin B(1) |
title_short | Effects of tannic acid on growth performance, relative organ weight, antioxidative status, and intestinal histomorphology in broilers exposed to aflatoxin B(1) |
title_sort | effects of tannic acid on growth performance, relative organ weight, antioxidative status, and intestinal histomorphology in broilers exposed to aflatoxin b(1) |
topic | Veterinary Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634217/ https://www.ncbi.nlm.nih.gov/pubmed/36337182 http://dx.doi.org/10.3389/fvets.2022.1037046 |
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