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Spinal Cord Infarction After Transarterial Chemoembolization for Hepatocellular Carcinoma

Transarterial chemoembolization (TACE) is an effective treatment for unresectable hepatocellular carcinoma (HCC). It is considered relatively safe. However, fatal complications such as pulmonary edema and liver abscesses can occur. Spinal infarction due to local embolism of the central nervous syste...

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Autores principales: Lee, Sang-Geun, Cho, Sung Min, Whang, Kum, Jang, Yeon gyu, Kim, Jongyeon, Choi, Jongwook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Neurotraumatology Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634294/
https://www.ncbi.nlm.nih.gov/pubmed/36381448
http://dx.doi.org/10.13004/kjnt.2022.18.e65
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author Lee, Sang-Geun
Cho, Sung Min
Whang, Kum
Jang, Yeon gyu
Kim, Jongyeon
Choi, Jongwook
author_facet Lee, Sang-Geun
Cho, Sung Min
Whang, Kum
Jang, Yeon gyu
Kim, Jongyeon
Choi, Jongwook
author_sort Lee, Sang-Geun
collection PubMed
description Transarterial chemoembolization (TACE) is an effective treatment for unresectable hepatocellular carcinoma (HCC). It is considered relatively safe. However, fatal complications such as pulmonary edema and liver abscesses can occur. Spinal infarction due to local embolism of the central nervous system after TACE is a very rare, but fatal complication. Here, we report a case of spinal cord infarction after TACE for ruptured HCC. Paraplegia occurred at the T10 sensory level 6 hours after the procedure. The patient received steroid megadose therapy but died 5 days later due to exacerbation of metabolic acidosis and blood loss. This case demonstrates the need for a comprehensive and extensive study of arterial blood flow prior to angiography.
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spelling pubmed-96342942022-11-14 Spinal Cord Infarction After Transarterial Chemoembolization for Hepatocellular Carcinoma Lee, Sang-Geun Cho, Sung Min Whang, Kum Jang, Yeon gyu Kim, Jongyeon Choi, Jongwook Korean J Neurotrauma Current Issue Transarterial chemoembolization (TACE) is an effective treatment for unresectable hepatocellular carcinoma (HCC). It is considered relatively safe. However, fatal complications such as pulmonary edema and liver abscesses can occur. Spinal infarction due to local embolism of the central nervous system after TACE is a very rare, but fatal complication. Here, we report a case of spinal cord infarction after TACE for ruptured HCC. Paraplegia occurred at the T10 sensory level 6 hours after the procedure. The patient received steroid megadose therapy but died 5 days later due to exacerbation of metabolic acidosis and blood loss. This case demonstrates the need for a comprehensive and extensive study of arterial blood flow prior to angiography. Korean Neurotraumatology Society 2022-10-25 /pmc/articles/PMC9634294/ /pubmed/36381448 http://dx.doi.org/10.13004/kjnt.2022.18.e65 Text en Copyright © 2022 Korean Neurotraumatology Society https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Current Issue
Lee, Sang-Geun
Cho, Sung Min
Whang, Kum
Jang, Yeon gyu
Kim, Jongyeon
Choi, Jongwook
Spinal Cord Infarction After Transarterial Chemoembolization for Hepatocellular Carcinoma
title Spinal Cord Infarction After Transarterial Chemoembolization for Hepatocellular Carcinoma
title_full Spinal Cord Infarction After Transarterial Chemoembolization for Hepatocellular Carcinoma
title_fullStr Spinal Cord Infarction After Transarterial Chemoembolization for Hepatocellular Carcinoma
title_full_unstemmed Spinal Cord Infarction After Transarterial Chemoembolization for Hepatocellular Carcinoma
title_short Spinal Cord Infarction After Transarterial Chemoembolization for Hepatocellular Carcinoma
title_sort spinal cord infarction after transarterial chemoembolization for hepatocellular carcinoma
topic Current Issue
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634294/
https://www.ncbi.nlm.nih.gov/pubmed/36381448
http://dx.doi.org/10.13004/kjnt.2022.18.e65
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