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Preventable mortality among sexual minority Canadians

BACKGROUND: Epidemiologic studies point to multiple health inequities among sexual minority people, but few studies have examined mortality. Some causes of death are more preventable than others, and access to prevention is theorized to follow patterns of access to social and material resources. The...

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Autores principales: Salway, Travis, Rich, Ashleigh J., Ferlatte, Olivier, Gesink, Dionne, Ross, Lori E., Bränström, Richard, Sadr, Aida, Khan, Syma, Grennan, Troy, Shokoohi, Mostafa, Brennan, David J., Gilbert, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634359/
https://www.ncbi.nlm.nih.gov/pubmed/36337988
http://dx.doi.org/10.1016/j.ssmph.2022.101276
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author Salway, Travis
Rich, Ashleigh J.
Ferlatte, Olivier
Gesink, Dionne
Ross, Lori E.
Bränström, Richard
Sadr, Aida
Khan, Syma
Grennan, Troy
Shokoohi, Mostafa
Brennan, David J.
Gilbert, Mark
author_facet Salway, Travis
Rich, Ashleigh J.
Ferlatte, Olivier
Gesink, Dionne
Ross, Lori E.
Bränström, Richard
Sadr, Aida
Khan, Syma
Grennan, Troy
Shokoohi, Mostafa
Brennan, David J.
Gilbert, Mark
author_sort Salway, Travis
collection PubMed
description BACKGROUND: Epidemiologic studies point to multiple health inequities among sexual minority people, but few studies have examined mortality. Some causes of death are more preventable than others, and access to prevention is theorized to follow patterns of access to social and material resources. The objective of this study is to compare estimates of preventable mortality between sexual minority (SM)—i.e., bisexual, lesbian, gay—and heterosexual adults in Canada. METHODS: A population-based retrospective cohort with 442,260 (unweighted N) Canadian adults, ages 18–59 years, was drawn from the Canadian Community Health Survey/Canadian Mortality Database linked database (2003–2017). The Rutstein preventability rating index was used to classify cause-specific mortality (low/high). Longitudinal analyses were conducted using Cox proportional hazards models. RESULTS: SM respondents had higher hazard of all-cause mortality (unadjusted hazard ratio [uHR] 1.28, 95% CI 1.06, 1.55). The uHR increased when the outcome was limited to highly-preventable causes of mortality (uHR 1.43, 95% CI 1.14, 1.80). The uHR further increased in sensitivity analyses using higher thresholds of the Rutstein index. SM respondents had higher hazard of cause-specific mortality for heart disease (uHR 1.53, 95% CI 1.03, 2.29), accidents (uHR 1.97, 95% CI 1.01, 3.86), HIV (uHR 75.69, 95% CI 18.77, 305.20), and suicide (uHR 2.22, 95% CI 0.93, 5.30) but not for cancer (uHR 0.86, 95% CI 0.60, 1.25). The adjusted HR (aHR) for highly-preventable mortality was not attenuated by adjustment for confounders (aHR 1.57, 95% CI 1.20, 2.05) but was reduced by adjustment for hypothesized mediators relating to access to social and material resources (marital status, children, income, education; aHR 1.11, 95% CI 0.78, 1.58). CONCLUSIONS: Preventable mortality was elevated for SM Canadians compared to heterosexuals. Early and broad access to sexual minority-affirming primary and preventive healthcare should be expanded.
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spelling pubmed-96343592022-11-05 Preventable mortality among sexual minority Canadians Salway, Travis Rich, Ashleigh J. Ferlatte, Olivier Gesink, Dionne Ross, Lori E. Bränström, Richard Sadr, Aida Khan, Syma Grennan, Troy Shokoohi, Mostafa Brennan, David J. Gilbert, Mark SSM Popul Health Regular Article BACKGROUND: Epidemiologic studies point to multiple health inequities among sexual minority people, but few studies have examined mortality. Some causes of death are more preventable than others, and access to prevention is theorized to follow patterns of access to social and material resources. The objective of this study is to compare estimates of preventable mortality between sexual minority (SM)—i.e., bisexual, lesbian, gay—and heterosexual adults in Canada. METHODS: A population-based retrospective cohort with 442,260 (unweighted N) Canadian adults, ages 18–59 years, was drawn from the Canadian Community Health Survey/Canadian Mortality Database linked database (2003–2017). The Rutstein preventability rating index was used to classify cause-specific mortality (low/high). Longitudinal analyses were conducted using Cox proportional hazards models. RESULTS: SM respondents had higher hazard of all-cause mortality (unadjusted hazard ratio [uHR] 1.28, 95% CI 1.06, 1.55). The uHR increased when the outcome was limited to highly-preventable causes of mortality (uHR 1.43, 95% CI 1.14, 1.80). The uHR further increased in sensitivity analyses using higher thresholds of the Rutstein index. SM respondents had higher hazard of cause-specific mortality for heart disease (uHR 1.53, 95% CI 1.03, 2.29), accidents (uHR 1.97, 95% CI 1.01, 3.86), HIV (uHR 75.69, 95% CI 18.77, 305.20), and suicide (uHR 2.22, 95% CI 0.93, 5.30) but not for cancer (uHR 0.86, 95% CI 0.60, 1.25). The adjusted HR (aHR) for highly-preventable mortality was not attenuated by adjustment for confounders (aHR 1.57, 95% CI 1.20, 2.05) but was reduced by adjustment for hypothesized mediators relating to access to social and material resources (marital status, children, income, education; aHR 1.11, 95% CI 0.78, 1.58). CONCLUSIONS: Preventable mortality was elevated for SM Canadians compared to heterosexuals. Early and broad access to sexual minority-affirming primary and preventive healthcare should be expanded. Elsevier 2022-10-27 /pmc/articles/PMC9634359/ /pubmed/36337988 http://dx.doi.org/10.1016/j.ssmph.2022.101276 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Regular Article
Salway, Travis
Rich, Ashleigh J.
Ferlatte, Olivier
Gesink, Dionne
Ross, Lori E.
Bränström, Richard
Sadr, Aida
Khan, Syma
Grennan, Troy
Shokoohi, Mostafa
Brennan, David J.
Gilbert, Mark
Preventable mortality among sexual minority Canadians
title Preventable mortality among sexual minority Canadians
title_full Preventable mortality among sexual minority Canadians
title_fullStr Preventable mortality among sexual minority Canadians
title_full_unstemmed Preventable mortality among sexual minority Canadians
title_short Preventable mortality among sexual minority Canadians
title_sort preventable mortality among sexual minority canadians
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634359/
https://www.ncbi.nlm.nih.gov/pubmed/36337988
http://dx.doi.org/10.1016/j.ssmph.2022.101276
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