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Preventable mortality among sexual minority Canadians
BACKGROUND: Epidemiologic studies point to multiple health inequities among sexual minority people, but few studies have examined mortality. Some causes of death are more preventable than others, and access to prevention is theorized to follow patterns of access to social and material resources. The...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634359/ https://www.ncbi.nlm.nih.gov/pubmed/36337988 http://dx.doi.org/10.1016/j.ssmph.2022.101276 |
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author | Salway, Travis Rich, Ashleigh J. Ferlatte, Olivier Gesink, Dionne Ross, Lori E. Bränström, Richard Sadr, Aida Khan, Syma Grennan, Troy Shokoohi, Mostafa Brennan, David J. Gilbert, Mark |
author_facet | Salway, Travis Rich, Ashleigh J. Ferlatte, Olivier Gesink, Dionne Ross, Lori E. Bränström, Richard Sadr, Aida Khan, Syma Grennan, Troy Shokoohi, Mostafa Brennan, David J. Gilbert, Mark |
author_sort | Salway, Travis |
collection | PubMed |
description | BACKGROUND: Epidemiologic studies point to multiple health inequities among sexual minority people, but few studies have examined mortality. Some causes of death are more preventable than others, and access to prevention is theorized to follow patterns of access to social and material resources. The objective of this study is to compare estimates of preventable mortality between sexual minority (SM)—i.e., bisexual, lesbian, gay—and heterosexual adults in Canada. METHODS: A population-based retrospective cohort with 442,260 (unweighted N) Canadian adults, ages 18–59 years, was drawn from the Canadian Community Health Survey/Canadian Mortality Database linked database (2003–2017). The Rutstein preventability rating index was used to classify cause-specific mortality (low/high). Longitudinal analyses were conducted using Cox proportional hazards models. RESULTS: SM respondents had higher hazard of all-cause mortality (unadjusted hazard ratio [uHR] 1.28, 95% CI 1.06, 1.55). The uHR increased when the outcome was limited to highly-preventable causes of mortality (uHR 1.43, 95% CI 1.14, 1.80). The uHR further increased in sensitivity analyses using higher thresholds of the Rutstein index. SM respondents had higher hazard of cause-specific mortality for heart disease (uHR 1.53, 95% CI 1.03, 2.29), accidents (uHR 1.97, 95% CI 1.01, 3.86), HIV (uHR 75.69, 95% CI 18.77, 305.20), and suicide (uHR 2.22, 95% CI 0.93, 5.30) but not for cancer (uHR 0.86, 95% CI 0.60, 1.25). The adjusted HR (aHR) for highly-preventable mortality was not attenuated by adjustment for confounders (aHR 1.57, 95% CI 1.20, 2.05) but was reduced by adjustment for hypothesized mediators relating to access to social and material resources (marital status, children, income, education; aHR 1.11, 95% CI 0.78, 1.58). CONCLUSIONS: Preventable mortality was elevated for SM Canadians compared to heterosexuals. Early and broad access to sexual minority-affirming primary and preventive healthcare should be expanded. |
format | Online Article Text |
id | pubmed-9634359 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-96343592022-11-05 Preventable mortality among sexual minority Canadians Salway, Travis Rich, Ashleigh J. Ferlatte, Olivier Gesink, Dionne Ross, Lori E. Bränström, Richard Sadr, Aida Khan, Syma Grennan, Troy Shokoohi, Mostafa Brennan, David J. Gilbert, Mark SSM Popul Health Regular Article BACKGROUND: Epidemiologic studies point to multiple health inequities among sexual minority people, but few studies have examined mortality. Some causes of death are more preventable than others, and access to prevention is theorized to follow patterns of access to social and material resources. The objective of this study is to compare estimates of preventable mortality between sexual minority (SM)—i.e., bisexual, lesbian, gay—and heterosexual adults in Canada. METHODS: A population-based retrospective cohort with 442,260 (unweighted N) Canadian adults, ages 18–59 years, was drawn from the Canadian Community Health Survey/Canadian Mortality Database linked database (2003–2017). The Rutstein preventability rating index was used to classify cause-specific mortality (low/high). Longitudinal analyses were conducted using Cox proportional hazards models. RESULTS: SM respondents had higher hazard of all-cause mortality (unadjusted hazard ratio [uHR] 1.28, 95% CI 1.06, 1.55). The uHR increased when the outcome was limited to highly-preventable causes of mortality (uHR 1.43, 95% CI 1.14, 1.80). The uHR further increased in sensitivity analyses using higher thresholds of the Rutstein index. SM respondents had higher hazard of cause-specific mortality for heart disease (uHR 1.53, 95% CI 1.03, 2.29), accidents (uHR 1.97, 95% CI 1.01, 3.86), HIV (uHR 75.69, 95% CI 18.77, 305.20), and suicide (uHR 2.22, 95% CI 0.93, 5.30) but not for cancer (uHR 0.86, 95% CI 0.60, 1.25). The adjusted HR (aHR) for highly-preventable mortality was not attenuated by adjustment for confounders (aHR 1.57, 95% CI 1.20, 2.05) but was reduced by adjustment for hypothesized mediators relating to access to social and material resources (marital status, children, income, education; aHR 1.11, 95% CI 0.78, 1.58). CONCLUSIONS: Preventable mortality was elevated for SM Canadians compared to heterosexuals. Early and broad access to sexual minority-affirming primary and preventive healthcare should be expanded. Elsevier 2022-10-27 /pmc/articles/PMC9634359/ /pubmed/36337988 http://dx.doi.org/10.1016/j.ssmph.2022.101276 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Regular Article Salway, Travis Rich, Ashleigh J. Ferlatte, Olivier Gesink, Dionne Ross, Lori E. Bränström, Richard Sadr, Aida Khan, Syma Grennan, Troy Shokoohi, Mostafa Brennan, David J. Gilbert, Mark Preventable mortality among sexual minority Canadians |
title | Preventable mortality among sexual minority Canadians |
title_full | Preventable mortality among sexual minority Canadians |
title_fullStr | Preventable mortality among sexual minority Canadians |
title_full_unstemmed | Preventable mortality among sexual minority Canadians |
title_short | Preventable mortality among sexual minority Canadians |
title_sort | preventable mortality among sexual minority canadians |
topic | Regular Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634359/ https://www.ncbi.nlm.nih.gov/pubmed/36337988 http://dx.doi.org/10.1016/j.ssmph.2022.101276 |
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