Structural variants identified using non-Mendelian inheritance patterns advance the mechanistic understanding of autism spectrum disorder

The heritability of autism spectrum disorder (ASD), based on 680,000 families and five countries, is estimated to be nearly 80%, yet heritability reported from SNP-based studies are consistently lower, and few significant loci have been identified with genome-wide association studies. This gap in ge...

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Detalles Bibliográficos
Autores principales: Kainer, David, Templeton, Alan R., Prates, Erica T., Jacboson, Daniel, Allan, Euan R.O., Climer, Sharlee, Garvin, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634371/
https://www.ncbi.nlm.nih.gov/pubmed/36340933
http://dx.doi.org/10.1016/j.xhgg.2022.100150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634371/
https://www.ncbi.nlm.nih.gov/pubmed/36340933
http://dx.doi.org/10.1016/j.xhgg.2022.100150

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