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Totally percutaneous endovascular repair for ruptured abdominal aortic aneurysms

PURPOSE: The PEVAR Trial demonstrated that compared to open femoral exposure, elective percutaneous endovascular AAA repair (ePEVAR) is associated with decreased perioperative morbidity and access site complications. We hypothesized that PEVAR for ruptured AAA (rPEVAR) may also improve perioperative...

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Autores principales: Tay, Shirli, Zaghloul, Mohamed S., Shafqat, Mehreen, Yang, Chao, Desai, Kshitij A., De Silva, Gayan, Sanchez, Luis A., Zayed, Mohamed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634472/
https://www.ncbi.nlm.nih.gov/pubmed/36338637
http://dx.doi.org/10.3389/fsurg.2022.1040929
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author Tay, Shirli
Zaghloul, Mohamed S.
Shafqat, Mehreen
Yang, Chao
Desai, Kshitij A.
De Silva, Gayan
Sanchez, Luis A.
Zayed, Mohamed A.
author_facet Tay, Shirli
Zaghloul, Mohamed S.
Shafqat, Mehreen
Yang, Chao
Desai, Kshitij A.
De Silva, Gayan
Sanchez, Luis A.
Zayed, Mohamed A.
author_sort Tay, Shirli
collection PubMed
description PURPOSE: The PEVAR Trial demonstrated that compared to open femoral exposure, elective percutaneous endovascular AAA repair (ePEVAR) is associated with decreased perioperative morbidity and access site complications. We hypothesized that PEVAR for ruptured AAA (rPEVAR) may also improve perioperative morbidity compared to open femoral exposure (rEVAR). There are currently no reports that evaluate the utility and outcomes of rPEVAR. MATERIALS AND METHODS: From 2015 to 2021, all patients who underwent an endovascular repair of a ruptured AAA at a single institution were included in the study and grouped into rPEVAR and rEVAR. Demographics, procedural details (successful preclose technique, conversion to femoral cutdown), postoperative variables (blood transfusion, ICU and hospital length of stay) and short-term outcomes (30-day major adverse events (30-day MAE) and 30-day femoral access-site complications (30-day FAAC)) were collected and compared with 50 historical ePEVAR patients from the PEVAR Trial. Statistical significance was determined using χ(2) or Fisher's exact test for categorical variables, and Mann–Whitney U-test for continuous variables. RESULTS: 35 patients were identified (21 rPEVAR; 14 rEVAR), 86% were male with a mean age of 72 ± 9 years. All patients underwent emergent endovascular aortic repair with 100% technical success. Seventeen patients (49%) presented with evidence of hemorrhagic shock and 22 patients (63%) had blood transfusion. 30-day MAE occurred in 12 patients (34%) (7 rPEVAR; 5 rEVAR). There was no difference in demographic, perioperative outcomes and 30-day MAE rate between rPEVAR and rEVAR patients. Compared to ePEVAR patient (from PEVAR trial), rPEVAR patients had higher rate of 30-day MAE (34% vs. 6%; p < 0.006) but no difference in 30-day FAAC (19% vs. 12%; p = 0.54). The success rate of the preclose technique was higher in ePEVAR compared to rPEVAR (96% vs. 76%; p = 0.02), but the rate of conversion to femoral cutdown was similar between the two groups (10% vs. 4%; p = 0.57). CONCLUSION: Emergent rPEVAR appears to have similar outcomes when compared to rEVAR. Although patients undergoing rPEVAR have higher 30-day major adverse events rate compared to ePEVAR, the method of percutaneous femoral cannulation does not appear to increase the overall procedural or 30-day femoral artery access-site complications.
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spelling pubmed-96344722022-11-05 Totally percutaneous endovascular repair for ruptured abdominal aortic aneurysms Tay, Shirli Zaghloul, Mohamed S. Shafqat, Mehreen Yang, Chao Desai, Kshitij A. De Silva, Gayan Sanchez, Luis A. Zayed, Mohamed A. Front Surg Surgery PURPOSE: The PEVAR Trial demonstrated that compared to open femoral exposure, elective percutaneous endovascular AAA repair (ePEVAR) is associated with decreased perioperative morbidity and access site complications. We hypothesized that PEVAR for ruptured AAA (rPEVAR) may also improve perioperative morbidity compared to open femoral exposure (rEVAR). There are currently no reports that evaluate the utility and outcomes of rPEVAR. MATERIALS AND METHODS: From 2015 to 2021, all patients who underwent an endovascular repair of a ruptured AAA at a single institution were included in the study and grouped into rPEVAR and rEVAR. Demographics, procedural details (successful preclose technique, conversion to femoral cutdown), postoperative variables (blood transfusion, ICU and hospital length of stay) and short-term outcomes (30-day major adverse events (30-day MAE) and 30-day femoral access-site complications (30-day FAAC)) were collected and compared with 50 historical ePEVAR patients from the PEVAR Trial. Statistical significance was determined using χ(2) or Fisher's exact test for categorical variables, and Mann–Whitney U-test for continuous variables. RESULTS: 35 patients were identified (21 rPEVAR; 14 rEVAR), 86% were male with a mean age of 72 ± 9 years. All patients underwent emergent endovascular aortic repair with 100% technical success. Seventeen patients (49%) presented with evidence of hemorrhagic shock and 22 patients (63%) had blood transfusion. 30-day MAE occurred in 12 patients (34%) (7 rPEVAR; 5 rEVAR). There was no difference in demographic, perioperative outcomes and 30-day MAE rate between rPEVAR and rEVAR patients. Compared to ePEVAR patient (from PEVAR trial), rPEVAR patients had higher rate of 30-day MAE (34% vs. 6%; p < 0.006) but no difference in 30-day FAAC (19% vs. 12%; p = 0.54). The success rate of the preclose technique was higher in ePEVAR compared to rPEVAR (96% vs. 76%; p = 0.02), but the rate of conversion to femoral cutdown was similar between the two groups (10% vs. 4%; p = 0.57). CONCLUSION: Emergent rPEVAR appears to have similar outcomes when compared to rEVAR. Although patients undergoing rPEVAR have higher 30-day major adverse events rate compared to ePEVAR, the method of percutaneous femoral cannulation does not appear to increase the overall procedural or 30-day femoral artery access-site complications. Frontiers Media S.A. 2022-10-21 /pmc/articles/PMC9634472/ /pubmed/36338637 http://dx.doi.org/10.3389/fsurg.2022.1040929 Text en © 2022 Tay, Zaghloul, Shafqat, Yang, Desai, De Silva, Sanchez and Zayed. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Tay, Shirli
Zaghloul, Mohamed S.
Shafqat, Mehreen
Yang, Chao
Desai, Kshitij A.
De Silva, Gayan
Sanchez, Luis A.
Zayed, Mohamed A.
Totally percutaneous endovascular repair for ruptured abdominal aortic aneurysms
title Totally percutaneous endovascular repair for ruptured abdominal aortic aneurysms
title_full Totally percutaneous endovascular repair for ruptured abdominal aortic aneurysms
title_fullStr Totally percutaneous endovascular repair for ruptured abdominal aortic aneurysms
title_full_unstemmed Totally percutaneous endovascular repair for ruptured abdominal aortic aneurysms
title_short Totally percutaneous endovascular repair for ruptured abdominal aortic aneurysms
title_sort totally percutaneous endovascular repair for ruptured abdominal aortic aneurysms
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634472/
https://www.ncbi.nlm.nih.gov/pubmed/36338637
http://dx.doi.org/10.3389/fsurg.2022.1040929
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