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Integrative genomic analysis of drug resistance in MET exon 14 skipping lung cancer using patient-derived xenograft models

BACKGROUND: Non-small cell lung cancer (NSCLC) driven by MET exon 14 skipping (METex14) occurs in 3-4% of NSCLC cases and defines a subset of patients with distinct characteristics. While MET targeted therapy has led to strong clinical results in METex14 patients, acquired drug resistance seemed to...

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Detalles Bibliográficos
Autores principales:	Xu, Yunhua, Gu, Linping, Li, Yingqi, Zhao, Ruiying, Jian, Hong, Xie, Wenhui, Liu, Liu, Wu, Huiwen, Ren, Fang, Han, Yuchen, Lu, Shun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634635/ https://www.ncbi.nlm.nih.gov/pubmed/36338758 http://dx.doi.org/10.3389/fonc.2022.1024818

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