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A Potential Role for Aminoacylation in Primordial RNA Copying Chemistry

[Image: see text] Aminoacylated tRNAs are the substrates for ribosomal protein synthesis in all branches of life, implying an ancient origin for aminoacylation chemistry. In the 1970s, Orgel and colleagues reported potentially prebiotic routes to aminoacylated nucleotides and their RNA-templated con...

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Detalles Bibliográficos
Autores principales: Radakovic, Aleksandar, Wright, Tom H., Lelyveld, Victor S., Szostak, Jack W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634692/
https://www.ncbi.nlm.nih.gov/pubmed/33523633
http://dx.doi.org/10.1021/acs.biochem.0c00943