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Identification of the outcome distribution and sensitivity analysis under weak confounder–instrument interaction

Recently, Wang and Tchetgen Tchetgen (2018) showed that the global average treatment effect is identifiable even in the presence of unmeasured confounders so long as they do not modify the instrument’s additive effect on the treatment. We use a simple and direct method to show that this no-interacti...

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Autor principal: Mao, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634714/
https://www.ncbi.nlm.nih.gov/pubmed/36337258
http://dx.doi.org/10.1016/j.spl.2022.109590
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author Mao, Lu
author_facet Mao, Lu
author_sort Mao, Lu
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description Recently, Wang and Tchetgen Tchetgen (2018) showed that the global average treatment effect is identifiable even in the presence of unmeasured confounders so long as they do not modify the instrument’s additive effect on the treatment. We use a simple and direct method to show that this no-interaction assumption allows identification of the entire outcome distribution, which leads to multiply robust estimation procedures for nonlinear functionals like the quantile and Mann–Whitney treatment effects. Similarly, we can bound these causal estimands through the outcome distribution in sensitivity analysis against confounder–instrument interaction.
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spelling pubmed-96347142022-11-04 Identification of the outcome distribution and sensitivity analysis under weak confounder–instrument interaction Mao, Lu Stat Probab Lett Article Recently, Wang and Tchetgen Tchetgen (2018) showed that the global average treatment effect is identifiable even in the presence of unmeasured confounders so long as they do not modify the instrument’s additive effect on the treatment. We use a simple and direct method to show that this no-interaction assumption allows identification of the entire outcome distribution, which leads to multiply robust estimation procedures for nonlinear functionals like the quantile and Mann–Whitney treatment effects. Similarly, we can bound these causal estimands through the outcome distribution in sensitivity analysis against confounder–instrument interaction. 2022-10 2022-06-23 /pmc/articles/PMC9634714/ /pubmed/36337258 http://dx.doi.org/10.1016/j.spl.2022.109590 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ).
spellingShingle Article
Mao, Lu
Identification of the outcome distribution and sensitivity analysis under weak confounder–instrument interaction
title Identification of the outcome distribution and sensitivity analysis under weak confounder–instrument interaction
title_full Identification of the outcome distribution and sensitivity analysis under weak confounder–instrument interaction
title_fullStr Identification of the outcome distribution and sensitivity analysis under weak confounder–instrument interaction
title_full_unstemmed Identification of the outcome distribution and sensitivity analysis under weak confounder–instrument interaction
title_short Identification of the outcome distribution and sensitivity analysis under weak confounder–instrument interaction
title_sort identification of the outcome distribution and sensitivity analysis under weak confounder–instrument interaction
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634714/
https://www.ncbi.nlm.nih.gov/pubmed/36337258
http://dx.doi.org/10.1016/j.spl.2022.109590
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