Cargando…
Propofol attenuates kinesin-mediated axonal vesicle transport and fusion
Propofol is a widely used general anesthetic, yet the understanding of its cellular effects is fragmentary. General anesthetics are not as innocuous as once believed and have a wide range of molecular targets that include kinesin motors. Propofol, ketamine, and etomidate reduce the distances that Ki...
Autores principales: | Frank, Madeline, Nabb, Alec T., Gilbert, Susan P., Bentley, Marvin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634964/ https://www.ncbi.nlm.nih.gov/pubmed/36103253 http://dx.doi.org/10.1091/mbc.E22-07-0276 |
Ejemplares similares
-
NgCAM and VAMP2 reveal that direct delivery and dendritic degradation maintain axonal polarity
por: Nabb, Alec T., et al.
Publicado: (2022) -
An allosteric propofol-binding site in kinesin disrupts kinesin-mediated processive movement on microtubules
por: Woll, Kellie A., et al.
Publicado: (2018) -
Axonal transport of Frizzled5 by Alcadein α-containing vesicles is associated with kinesin-1
por: Shiraki, Yuzuha, et al.
Publicado: (2023) -
Unc-51/ATG1 Controls Axonal and Dendritic Development via Kinesin-Mediated Vesicle Transport in the Drosophila Brain
por: Mochizuki, Hiroaki, et al.
Publicado: (2011) -
Kinesin Light Chains Are Essential for Axonal Transport in Drosophila
por: Gindhart, Joseph G., et al.
Publicado: (1998)