Cargando…

CEP19–RABL2–IFT-B axis controls BBSome-mediated ciliary GPCR export

The intraflagellar transport (IFT) machinery mediates the import and export of ciliary proteins across the ciliary gate, as well as bidirectional protein trafficking within cilia. In addition to ciliary anterograde protein trafficking, the IFT-B complex participates in the export of membrane protein...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Zhuang, Katoh, Yohei, Nakayama, Kazuhisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634966/ https://www.ncbi.nlm.nih.gov/pubmed/36074075 http://dx.doi.org/10.1091/mbc.E22-05-0161

Ejemplares similares

Requirement of IFT-B–BBSome complex interaction in export of GPR161 from cilia
por: Nozaki, Shohei, et al.
Publicado: (2019)

RABL2 interacts with the intraflagellar transport-B complex and CEP19 and participates in ciliary assembly
por: Nishijima, Yuya, et al.
Publicado: (2017)

Cooperation of the IFT-A complex with the IFT-B complex is required for ciliary retrograde protein trafficking and GPCR import
por: Kobayashi, Takuya, et al.
Publicado: (2021)

BBS1 is involved in retrograde trafficking of ciliary GPCRs in the context of the BBSome complex
por: Nozaki, Shohei, et al.
Publicado: (2018)

Robust interaction of IFT70 with IFT52–IFT88 in the IFT-B complex is required for ciliogenesis
por: Takei, Ryota, et al.
Publicado: (2018)

Ciliary entry of KIF17 is dependent on its binding to the IFT-B complex via IFT46–IFT56 as well as on its nuclear localization signal
por: Funabashi, Teruki, et al.
Publicado: (2017)

Chlamydomonas IFT25 is dispensable for flagellar assembly but required to export the BBSome from flagella
por: Dong, Bin, et al.
Publicado: (2017)

Molecular basis underlying the ciliary defects caused by IFT52 variations found in skeletal ciliopathies
por: Ishida, Yamato, et al.
Publicado: (2022)

The Chlamydomonas reinhardtii BBSome is an IFT cargo required for export of specific signaling proteins from flagella
por: Lechtreck, Karl-Ferdinand, et al.
Publicado: (2009)

The BBSome controls IFT assembly and turnaround in cilia
por: Wei, Qing, et al.
Publicado: (2012)

The BBSome’s export duty
por: Short, Ben
Publicado: (2013)

Assembly and stability of IFT-B complex and its function in BBSome trafficking
por: Wang, Jieling, et al.
Publicado: (2022)

The Meckel syndrome- associated protein MKS1 functionally interacts with components of the BBSome and IFT complexes to mediate ciliary trafficking and hedgehog signaling
por: Goetz, Sarah C., et al.
Publicado: (2017)

Near-atomic structures of the BBSome reveal the basis for BBSome activation and binding to GPCR cargoes
por: Yang, Shuang, et al.
Publicado: (2020)

Deletion of CEP164 in mouse photoreceptors post-ciliogenesis interrupts ciliary intraflagellar transport (IFT)
por: Reed, Michelle, et al.
Publicado: (2022)

Dynein-2–driven intraciliary retrograde trafficking indirectly requires multiple interactions of IFT54 in the IFT-B complex with the dynein-2 complex
por: Hiyamizu, Shunya, et al.
Publicado: (2023)

Interaction of heterotrimeric kinesin-II with IFT-B–connecting tetramer is crucial for ciliogenesis
por: Funabashi, Teruki, et al.
Publicado: (2018)

Intraflagellar transport-A complex mediates ciliary entry and retrograde trafficking of ciliary G protein–coupled receptors
por: Hirano, Tomoaki, et al.
Publicado: (2017)

The IFT81‐IFT74 complex acts as an unconventional RabL2 GTPase‐activating protein during intraflagellar transport
por: Boegholm, Niels, et al.
Publicado: (2023)

Ubiquitylation of BBSome is required for ciliary assembly and signaling
por: Chiuso, Francesco, et al.
Publicado: (2023)

Unraveling the intricate cargo-BBSome coupling mechanism at the ciliary tip
por: Liu, Yan-Xia, et al.
Publicado: (2023)

Interaction of INPP5E with ARL13B is essential for its ciliary membrane retention but dispensable for its ciliary entry
por: Qiu, Hantian, et al.
Publicado: (2021)

Dynamics of the IFT machinery at the ciliary tip
por: Chien, Alexander, et al.
Publicado: (2017)

A recombinant BBSome core complex and how it interacts with ciliary cargo
por: Klink, Björn Udo, et al.
Publicado: (2017)

Ciliary Rab28 and the BBSome negatively regulate extracellular vesicle shedding
por: Akella, Jyothi S, et al.
Publicado: (2020)

A Novel Protein LZTFL1 Regulates Ciliary Trafficking of the BBSome and Smoothened
por: Seo, Seongjin, et al.
Publicado: (2011)

ARL3 mediates BBSome ciliary turnover by promoting its outward movement across the transition zone
por: Liu, Yan-Xia, et al.
Publicado: (2022)

Multiple interactions of the dynein-2 complex with the IFT-B complex are required for effective intraflagellar transport
por: Hiyamizu, Shunya, et al.
Publicado: (2023)

The Intraflagellar Transport Protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3
por: Liew, G, et al.
Publicado: (2015)

Loss of ARL13 impedes BBSome-dependent cargo export from Chlamydomonas cilia
por: Dai, Jin, et al.
Publicado: (2022)

Interactions of the dynein-2 intermediate chain WDR34 with the light chains are required for ciliary retrograde protein trafficking
por: Tsurumi, Yuta, et al.
Publicado: (2019)

ARL3 and ARL13B GTPases participate in distinct steps of INPP5E targeting to the ciliary membrane
por: Fujisawa, Sayaka, et al.
Publicado: (2021)

The Centriolar Satellite Protein AZI1 Interacts with BBS4 and Regulates Ciliary Trafficking of the BBSome
por: Chamling, Xitiz, et al.
Publicado: (2014)

Cycling of the signaling protein phospholipase D through cilia requires the BBSome only for the export phase
por: Lechtreck, Karl F., et al.
Publicado: (2013)

Combinations of deletion and missense variations of the dynein-2 DYNC2LI1 subunit found in skeletal ciliopathies cause ciliary defects
por: Qiu, Hantian, et al.
Publicado: (2022)

WDR31 displays functional redundancy with GTPase-activating proteins (GAPs) ELMOD and RP2 in regulating IFT complex and recruiting the BBSome to cilium
por: Cevik, Sebiha, et al.
Publicado: (2023)

Building train carriages for ciliary transport: (IFT-)A complex task
por: Gonçalves-Santos, Francisco, et al.
Publicado: (2023)

CCRK/CDK20 regulates ciliary retrograde protein trafficking via interacting with BROMI/TBC1D32
por: Noguchi, Tatsuro, et al.
Publicado: (2021)

Formation of the B9-domain protein complex MKS1–B9D2–B9D1 is essential as a diffusion barrier for ciliary membrane proteins
por: Okazaki, Misato, et al.
Publicado: (2020)

Uni-directional ciliary membrane protein trafficking by a cytoplasmic retrograde IFT motor and ciliary ectosome shedding
por: Cao, Muqing, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_vhs63s0ci7encll8jvg51eq84q