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The endoplasmic reticulum contributes to lysosomal tubulation/sorting driven by LRRK2

Lysosomes are dynamic organelles that can remodel their membrane as an adaptive response to various cell signaling events including membrane damage. Recently, we have discovered that damaged lysosomes form and sort tubules into moving vesicles. We named this process LYTL for LYsosomal Tubulation/sor...

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Detalles Bibliográficos
Autores principales: Bonet-Ponce, Luis, Cookson, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634967/
https://www.ncbi.nlm.nih.gov/pubmed/36044336
http://dx.doi.org/10.1091/mbc.E22-04-0139