Cargando…
Spatiotemporal analysis of axonal autophagosome–lysosome dynamics reveals limited fusion events and slow maturation
Macroautophagy is a homeostatic process required to clear cellular waste. Neuronal autophagosomes form constitutively in the distal tip of the axon and are actively transported toward the soma, with cargo degradation initiated en route. Cargo turnover requires autophagosomes to fuse with lysosomes t...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634976/ https://www.ncbi.nlm.nih.gov/pubmed/36044338 http://dx.doi.org/10.1091/mbc.E22-03-0111 |