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Transgenic overexpression of α7 integrin in smooth muscle attenuates allergen‐induced airway inflammation in a murine model of asthma

Asthma is a chronic inflammatory disorder of the lower airways characterized by modulation of airway smooth muscle (ASM) function. Infiltration of smooth muscle by inflammatory mediators is partially regulated by transmembrane integrins and the major smooth muscle laminin receptor α7β1 integrin play...

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Detalles Bibliográficos
Autores principales: Ba, Mariam A., Aiyuk, Annemarie, Hernández, Karla, Evasovic, Jon M., Wuebbles, Ryan D., Burkin, Dean J., Singer, Cherie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635010/
https://www.ncbi.nlm.nih.gov/pubmed/36349295
http://dx.doi.org/10.1096/fba.2022-00050

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