Omicron BA.2.75 variant is efficiently neutralised following BA.1 and BA.5 breakthrough infection in vaccinated individuals, Israel, June to September 2022

We evaluated neutralising antibody titres against wild type (WT) SARS-CoV-2 and four Omicron variants (BA.1, BA.2, BA.5 and BA.2.75) in fully vaccinated (three doses of Comirnaty vaccine) healthcare workers (HCW) in Israel who had breakthrough BA.1/BA5 infections. Omicron breakthrough infections in...

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Autores principales: Atari, Nofar, Kliker, Limor, Zuckerman, Neta, Elkader, Bayan Abd, Weiss-Ottolenghi, Yael, Mendelson, Ella, Kreiss, Yitshak, Regev-Yochay, Gili, Mandelboim, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2022
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635020/
https://www.ncbi.nlm.nih.gov/pubmed/36330820
http://dx.doi.org/10.2807/1560-7917.ES.2022.27.44.2200785
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author Atari, Nofar
Kliker, Limor
Zuckerman, Neta
Elkader, Bayan Abd
Weiss-Ottolenghi, Yael
Mendelson, Ella
Kreiss, Yitshak
Regev-Yochay, Gili
Mandelboim, Michal
author_facet Atari, Nofar
Kliker, Limor
Zuckerman, Neta
Elkader, Bayan Abd
Weiss-Ottolenghi, Yael
Mendelson, Ella
Kreiss, Yitshak
Regev-Yochay, Gili
Mandelboim, Michal
author_sort Atari, Nofar
collection PubMed
description We evaluated neutralising antibody titres against wild type (WT) SARS-CoV-2 and four Omicron variants (BA.1, BA.2, BA.5 and BA.2.75) in fully vaccinated (three doses of Comirnaty vaccine) healthcare workers (HCW) in Israel who had breakthrough BA.1/BA5 infections. Omicron breakthrough infections in vaccinated individuals resulted in increased neutralising antibodies against the WT and Omicron variants compared with vaccinated uninfected HCW. HCW who recovered from BA.1 or BA.5 infections showed similar neutralising antibodies levels against BA.2.75.
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spelling pubmed-96350202022-11-07 Omicron BA.2.75 variant is efficiently neutralised following BA.1 and BA.5 breakthrough infection in vaccinated individuals, Israel, June to September 2022 Atari, Nofar Kliker, Limor Zuckerman, Neta Elkader, Bayan Abd Weiss-Ottolenghi, Yael Mendelson, Ella Kreiss, Yitshak Regev-Yochay, Gili Mandelboim, Michal Euro Surveill Rapid Communication We evaluated neutralising antibody titres against wild type (WT) SARS-CoV-2 and four Omicron variants (BA.1, BA.2, BA.5 and BA.2.75) in fully vaccinated (three doses of Comirnaty vaccine) healthcare workers (HCW) in Israel who had breakthrough BA.1/BA5 infections. Omicron breakthrough infections in vaccinated individuals resulted in increased neutralising antibodies against the WT and Omicron variants compared with vaccinated uninfected HCW. HCW who recovered from BA.1 or BA.5 infections showed similar neutralising antibodies levels against BA.2.75. European Centre for Disease Prevention and Control (ECDC) 2022-11-03 /pmc/articles/PMC9635020/ /pubmed/36330820 http://dx.doi.org/10.2807/1560-7917.ES.2022.27.44.2200785 Text en This article is copyright of the authors or their affiliated institutions, 2022. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Atari, Nofar
Kliker, Limor
Zuckerman, Neta
Elkader, Bayan Abd
Weiss-Ottolenghi, Yael
Mendelson, Ella
Kreiss, Yitshak
Regev-Yochay, Gili
Mandelboim, Michal
Omicron BA.2.75 variant is efficiently neutralised following BA.1 and BA.5 breakthrough infection in vaccinated individuals, Israel, June to September 2022
title Omicron BA.2.75 variant is efficiently neutralised following BA.1 and BA.5 breakthrough infection in vaccinated individuals, Israel, June to September 2022
title_full Omicron BA.2.75 variant is efficiently neutralised following BA.1 and BA.5 breakthrough infection in vaccinated individuals, Israel, June to September 2022
title_fullStr Omicron BA.2.75 variant is efficiently neutralised following BA.1 and BA.5 breakthrough infection in vaccinated individuals, Israel, June to September 2022
title_full_unstemmed Omicron BA.2.75 variant is efficiently neutralised following BA.1 and BA.5 breakthrough infection in vaccinated individuals, Israel, June to September 2022
title_short Omicron BA.2.75 variant is efficiently neutralised following BA.1 and BA.5 breakthrough infection in vaccinated individuals, Israel, June to September 2022
title_sort omicron ba.2.75 variant is efficiently neutralised following ba.1 and ba.5 breakthrough infection in vaccinated individuals, israel, june to september 2022
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635020/
https://www.ncbi.nlm.nih.gov/pubmed/36330820
http://dx.doi.org/10.2807/1560-7917.ES.2022.27.44.2200785
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