Ongoing toxin-positive diphtheria outbreaks in a federal asylum centre in Switzerland, analysis July to September 2022

Two diphtheria outbreaks occurred in a Swiss asylum center from July to October 2022, one is still ongoing. Outbreaks mainly involved minors and included six symptomatic respiratory diphtheria cases requiring antitoxin. Phylogenomic analyses showed evidence of imported and local transmissions of tox...

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Detalles Bibliográficos
Autores principales: Kofler, Jacob, Ramette, Alban, Iseli, Patricia, Stauber, Lea, Fichtner, Jens, Droz, Sara, Zihler Berner, Annina, Meier, Anna Bettina, Begert, Michelle, Negri, Sabine, Jachmann, Anne, Keller, Peter Michael, Staehelin, Cornelia, Grützmacher, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2022
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635023/
https://www.ncbi.nlm.nih.gov/pubmed/36330823
http://dx.doi.org/10.2807/1560-7917.ES.2022.27.44.2200811
Descripción
Sumario:Two diphtheria outbreaks occurred in a Swiss asylum center from July to October 2022, one is still ongoing. Outbreaks mainly involved minors and included six symptomatic respiratory diphtheria cases requiring antitoxin. Phylogenomic analyses showed evidence of imported and local transmissions of toxigenic strains in respiratory and skin lesion samples. Given the number of cases (n = 20) and the large genetic diversity accumulating in one centre, increased awareness and changes in public health measures are required to prevent and control diphtheria outbreaks.

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