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Severe acute malnutrition’s recovery rate still below the minimum standard: predictors of time to recovery among 6- to 59-month-old children in the healthcare setting of Southwest Ethiopia

BACKGROUND: Despite currently available, scientifically proven treatments and national guideline, the SAM recovery rate is still considerably behind expectations, and it continues to have a devastating impact on under-five children. Identifying predictors of time to recovery might help to reach the...

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Autores principales: Eyi, Seyum Ebissa, Debele, Gebiso Roba, Negash, Efrem, Bidira, Kebebe, Tarecha, Debela, Nigussie, Kabtamu, Hajure, Mohammedamin, Ahmed, Mohammedjud Hassen, Kefeni, Bilisumamulifna Tefera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635096/
https://www.ncbi.nlm.nih.gov/pubmed/36333768
http://dx.doi.org/10.1186/s41043-022-00331-9
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author Eyi, Seyum Ebissa
Debele, Gebiso Roba
Negash, Efrem
Bidira, Kebebe
Tarecha, Debela
Nigussie, Kabtamu
Hajure, Mohammedamin
Ahmed, Mohammedjud Hassen
Kefeni, Bilisumamulifna Tefera
author_facet Eyi, Seyum Ebissa
Debele, Gebiso Roba
Negash, Efrem
Bidira, Kebebe
Tarecha, Debela
Nigussie, Kabtamu
Hajure, Mohammedamin
Ahmed, Mohammedjud Hassen
Kefeni, Bilisumamulifna Tefera
author_sort Eyi, Seyum Ebissa
collection PubMed
description BACKGROUND: Despite currently available, scientifically proven treatments and national guideline, the SAM recovery rate is still considerably behind expectations, and it continues to have a devastating impact on under-five children. Identifying predictors of time to recovery might help to reach the minimal criterion established by the WHO and the national Sphere which decreases child mortality. Therefore, the current study assessed time to recovery and its predictors among children aged 6–59 months admitted with SAM in the Healthcare Setting of Southwest Ethiopia, 2021. METHODS: An institutional-based multicenter retrospective follow-up study was conducted on 486 children aged 6 to 59 months admitted with SAM cases. Data were entered into Epi-Data version 4.6 and exported to Stata version 14 for further analysis. Cox–Snell residual plot was used to assess the final model’s overall goodness of fit. Finally, a significant predictor of time to recovery was identified using Weibull survival regression model, at 0.05 significance level. RESULT: Overall, 68.72 (95% CI 64.8, 73) of the children recovered and 4.32% died. The overall incidence density was 3.35/100-person day. Independent predictors of time to recovery were, starting complementary feeding at six months (AHR = 1.44; 95%, CI 1.073, 1.935), pneumonia at baseline (AHR = 1.33, 95%, CI 1.049, 1.696), amoxicillin (AHR = 1.31, 95%, CI 1.021, 1.685), and folic acid supplementation (AHR = 1.82, 95% CI 1,237, 2.665). CONCLUSION: The recovery from SAM at study area after a maximum of 60 days of treatment was below the accepted minimum standard. Complementary feeding, pneumonia, treated by amoxicillin, and folic acid supplementation were predictors of time to recovery. Therefore, providing folic acid and amoxicillin for those in need as well as the earliest possible treatment of concomitant conditions like pneumonia is highly recommended. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s41043-022-00331-9.
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spelling pubmed-96350962022-11-05 Severe acute malnutrition’s recovery rate still below the minimum standard: predictors of time to recovery among 6- to 59-month-old children in the healthcare setting of Southwest Ethiopia Eyi, Seyum Ebissa Debele, Gebiso Roba Negash, Efrem Bidira, Kebebe Tarecha, Debela Nigussie, Kabtamu Hajure, Mohammedamin Ahmed, Mohammedjud Hassen Kefeni, Bilisumamulifna Tefera J Health Popul Nutr Research BACKGROUND: Despite currently available, scientifically proven treatments and national guideline, the SAM recovery rate is still considerably behind expectations, and it continues to have a devastating impact on under-five children. Identifying predictors of time to recovery might help to reach the minimal criterion established by the WHO and the national Sphere which decreases child mortality. Therefore, the current study assessed time to recovery and its predictors among children aged 6–59 months admitted with SAM in the Healthcare Setting of Southwest Ethiopia, 2021. METHODS: An institutional-based multicenter retrospective follow-up study was conducted on 486 children aged 6 to 59 months admitted with SAM cases. Data were entered into Epi-Data version 4.6 and exported to Stata version 14 for further analysis. Cox–Snell residual plot was used to assess the final model’s overall goodness of fit. Finally, a significant predictor of time to recovery was identified using Weibull survival regression model, at 0.05 significance level. RESULT: Overall, 68.72 (95% CI 64.8, 73) of the children recovered and 4.32% died. The overall incidence density was 3.35/100-person day. Independent predictors of time to recovery were, starting complementary feeding at six months (AHR = 1.44; 95%, CI 1.073, 1.935), pneumonia at baseline (AHR = 1.33, 95%, CI 1.049, 1.696), amoxicillin (AHR = 1.31, 95%, CI 1.021, 1.685), and folic acid supplementation (AHR = 1.82, 95% CI 1,237, 2.665). CONCLUSION: The recovery from SAM at study area after a maximum of 60 days of treatment was below the accepted minimum standard. Complementary feeding, pneumonia, treated by amoxicillin, and folic acid supplementation were predictors of time to recovery. Therefore, providing folic acid and amoxicillin for those in need as well as the earliest possible treatment of concomitant conditions like pneumonia is highly recommended. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s41043-022-00331-9. BioMed Central 2022-11-04 /pmc/articles/PMC9635096/ /pubmed/36333768 http://dx.doi.org/10.1186/s41043-022-00331-9 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Eyi, Seyum Ebissa
Debele, Gebiso Roba
Negash, Efrem
Bidira, Kebebe
Tarecha, Debela
Nigussie, Kabtamu
Hajure, Mohammedamin
Ahmed, Mohammedjud Hassen
Kefeni, Bilisumamulifna Tefera
Severe acute malnutrition’s recovery rate still below the minimum standard: predictors of time to recovery among 6- to 59-month-old children in the healthcare setting of Southwest Ethiopia
title Severe acute malnutrition’s recovery rate still below the minimum standard: predictors of time to recovery among 6- to 59-month-old children in the healthcare setting of Southwest Ethiopia
title_full Severe acute malnutrition’s recovery rate still below the minimum standard: predictors of time to recovery among 6- to 59-month-old children in the healthcare setting of Southwest Ethiopia
title_fullStr Severe acute malnutrition’s recovery rate still below the minimum standard: predictors of time to recovery among 6- to 59-month-old children in the healthcare setting of Southwest Ethiopia
title_full_unstemmed Severe acute malnutrition’s recovery rate still below the minimum standard: predictors of time to recovery among 6- to 59-month-old children in the healthcare setting of Southwest Ethiopia
title_short Severe acute malnutrition’s recovery rate still below the minimum standard: predictors of time to recovery among 6- to 59-month-old children in the healthcare setting of Southwest Ethiopia
title_sort severe acute malnutrition’s recovery rate still below the minimum standard: predictors of time to recovery among 6- to 59-month-old children in the healthcare setting of southwest ethiopia
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635096/
https://www.ncbi.nlm.nih.gov/pubmed/36333768
http://dx.doi.org/10.1186/s41043-022-00331-9
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