DNA methylome in pancreatic cancer identified novel promoter hyper-methylation in NPY and FAIM2 genes associated with poor prognosis in Indian patient cohort

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is one of the leading cancers worldwide and has a poor survival, with a 5-year survival rate of only 8.5%. In this study we investigated altered DNA methylation associated with PDAC severity and prognosis. METHODS: Methylome data, generated using 4...

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Detalles Bibliográficos
Autores principales: Chatterjee, Ankita, Bararia, Akash, Ganguly, Debopriyo, Mondal, Pronoy Kanti, Roy, Paromita, Banerjee, Sudeep, Ghosh, Shibajyoti, Gulati, Sumit, Ghatak, Supriyo, Chattopadhay, Bitan Kumar, Basu, Priyadarshi, Chatterjee, Aniruddha, Sikdar, Nilabja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635159/
https://www.ncbi.nlm.nih.gov/pubmed/36329447
http://dx.doi.org/10.1186/s12935-022-02737-1

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