Deficiency of exchange protein directly activated by cAMP (EPAC)-1 in mice augments glucose intolerance, inflammation, and gut dysbiosis associated with Western diet

BACKGROUND: Gut microbiota (GM) dysregulation, known as dysbiosis, has been proposed as a crucial driver of obesity associated with “Western” diet (WD) consumption. Gut dysbiosis is associated with increased gut permeability, inflammation, and insulin resistance. However, host metabolic pathways imp...

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Detalles Bibliográficos
Autores principales: Virwani, Preeti Dinesh, Cai, Lin, Yeung, Patrick Ka Kit, Qian, Gordon, Chen, Yingxian, Zhou, Lei, Wong, Jason Wing Hon, Wang, Yu, Ho, Joshua Wing Kei, Lau, Kui Kai, Qian, Pei-Yuan, Chung, Sookja Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635209/
https://www.ncbi.nlm.nih.gov/pubmed/36329549
http://dx.doi.org/10.1186/s40168-022-01366-0

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