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Stimuli-responsive transdermal microneedle patches
Microneedle (MN) patches consisting of miniature needles have emerged as a promising tool to perforate the stratum corneum and translocate biomolecules into the dermis in a minimally invasive manner. Stimuli-responsive MN patches represent emerging drug delivery systems that release cargos on-demand...
| Autores principales: | , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635273/ https://www.ncbi.nlm.nih.gov/pubmed/36338772 http://dx.doi.org/10.1016/j.mattod.2021.03.012 |
| _version_ | 1784824677590368256 |
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| author | Makvandi, Pooyan Jamaledin, Rezvan Chen, Guojun Baghbantaraghdari, Zahra Zare, Ehsan Nazarzadeh Di Natale, Concetta Onesto, Valentina Vecchione, Raffaele Lee, Jesse Tay, Franklin R. Netti, Paolo Mattoli, Virgilio Jaklenec, Ana Gu, Zhen Langer, Robert |
| author_facet | Makvandi, Pooyan Jamaledin, Rezvan Chen, Guojun Baghbantaraghdari, Zahra Zare, Ehsan Nazarzadeh Di Natale, Concetta Onesto, Valentina Vecchione, Raffaele Lee, Jesse Tay, Franklin R. Netti, Paolo Mattoli, Virgilio Jaklenec, Ana Gu, Zhen Langer, Robert |
| author_sort | Makvandi, Pooyan |
| collection | PubMed |
| description | Microneedle (MN) patches consisting of miniature needles have emerged as a promising tool to perforate the stratum corneum and translocate biomolecules into the dermis in a minimally invasive manner. Stimuli-responsive MN patches represent emerging drug delivery systems that release cargos on-demand as a response to internal or external triggers. In this review, a variety of stimuli-responsive MN patches for controlled drug release are introduced, covering the mechanisms of action toward different indications. Future opportunities and challenges with respect to clinical translation are also discussed. |
| format | Online Article Text |
| id | pubmed-9635273 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-96352732022-11-04 Stimuli-responsive transdermal microneedle patches Makvandi, Pooyan Jamaledin, Rezvan Chen, Guojun Baghbantaraghdari, Zahra Zare, Ehsan Nazarzadeh Di Natale, Concetta Onesto, Valentina Vecchione, Raffaele Lee, Jesse Tay, Franklin R. Netti, Paolo Mattoli, Virgilio Jaklenec, Ana Gu, Zhen Langer, Robert Mater Today (Kidlington) Article Microneedle (MN) patches consisting of miniature needles have emerged as a promising tool to perforate the stratum corneum and translocate biomolecules into the dermis in a minimally invasive manner. Stimuli-responsive MN patches represent emerging drug delivery systems that release cargos on-demand as a response to internal or external triggers. In this review, a variety of stimuli-responsive MN patches for controlled drug release are introduced, covering the mechanisms of action toward different indications. Future opportunities and challenges with respect to clinical translation are also discussed. 2021 2021-05-20 /pmc/articles/PMC9635273/ /pubmed/36338772 http://dx.doi.org/10.1016/j.mattod.2021.03.012 Text en https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ). |
| spellingShingle | Article Makvandi, Pooyan Jamaledin, Rezvan Chen, Guojun Baghbantaraghdari, Zahra Zare, Ehsan Nazarzadeh Di Natale, Concetta Onesto, Valentina Vecchione, Raffaele Lee, Jesse Tay, Franklin R. Netti, Paolo Mattoli, Virgilio Jaklenec, Ana Gu, Zhen Langer, Robert Stimuli-responsive transdermal microneedle patches |
| title | Stimuli-responsive transdermal microneedle patches |
| title_full | Stimuli-responsive transdermal microneedle patches |
| title_fullStr | Stimuli-responsive transdermal microneedle patches |
| title_full_unstemmed | Stimuli-responsive transdermal microneedle patches |
| title_short | Stimuli-responsive transdermal microneedle patches |
| title_sort | stimuli-responsive transdermal microneedle patches |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635273/ https://www.ncbi.nlm.nih.gov/pubmed/36338772 http://dx.doi.org/10.1016/j.mattod.2021.03.012 |
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