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Terminally differentiated osteoclasts organize centrosomes into large clusters for microtubule nucleation and bone resorption

Osteoclasts are highly specialized, multinucleated cells responsible for the selective resorption of the dense, calcified bone matrix. Microtubules (MTs) contribute to the polarization and trafficking events involved in bone resorption by osteoclasts; however, the origin of these elaborate arrays is...

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Detalles Bibliográficos
Autores principales: Philip, Reuben, Fiorino, Cara, Harrison, Rene E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635281/
https://www.ncbi.nlm.nih.gov/pubmed/35511803
http://dx.doi.org/10.1091/mbc.E22-03-0098