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Terminally differentiated osteoclasts organize centrosomes into large clusters for microtubule nucleation and bone resorption
Osteoclasts are highly specialized, multinucleated cells responsible for the selective resorption of the dense, calcified bone matrix. Microtubules (MTs) contribute to the polarization and trafficking events involved in bone resorption by osteoclasts; however, the origin of these elaborate arrays is...
Autores principales: | Philip, Reuben, Fiorino, Cara, Harrison, Rene E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635281/ https://www.ncbi.nlm.nih.gov/pubmed/35511803 http://dx.doi.org/10.1091/mbc.E22-03-0098 |
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