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Comprehensive Assessment of Anaplastic Lymphoma Kinase in Localized and Metastatic Prostate Cancer Reveals Targetable Alterations

Anaplastic lymphoma kinase (ALK) is a tyrosine kinase with genomic and expression changes in many solid tumors. ALK inhibition is the first-line therapy for lung cancers with ALK alterations, and an effective therapy in other tumor types, but has not been well-studied in prostate cancer. Here, we ai...

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Detalles Bibliográficos
Autores principales: Patel, Radhika A., Coleman, Ilsa, Roudier, Martine P., Konnick, Eric Q., Hanratty, Brian, Dumpit, Ruth, Lucas, Jared M., Ang, Lisa S., Low, Jin-Yih, Tretiakova, Maria S., Ha, Gavin, Lee, John K., True, Lawrence D., De Marzo, Angelo M., Nelson, Peter S., Morrissey, Colm, Pritchard, Colin C., Haffner, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635400/
https://www.ncbi.nlm.nih.gov/pubmed/36337169
http://dx.doi.org/10.1158/2767-9764.CRC-21-0156

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