Cargando…
Comprehensive Assessment of Anaplastic Lymphoma Kinase in Localized and Metastatic Prostate Cancer Reveals Targetable Alterations
Anaplastic lymphoma kinase (ALK) is a tyrosine kinase with genomic and expression changes in many solid tumors. ALK inhibition is the first-line therapy for lung cancers with ALK alterations, and an effective therapy in other tumor types, but has not been well-studied in prostate cancer. Here, we ai...
Autores principales: | Patel, Radhika A., Coleman, Ilsa, Roudier, Martine P., Konnick, Eric Q., Hanratty, Brian, Dumpit, Ruth, Lucas, Jared M., Ang, Lisa S., Low, Jin-Yih, Tretiakova, Maria S., Ha, Gavin, Lee, John K., True, Lawrence D., De Marzo, Angelo M., Nelson, Peter S., Morrissey, Colm, Pritchard, Colin C., Haffner, Michael C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635400/ https://www.ncbi.nlm.nih.gov/pubmed/36337169 http://dx.doi.org/10.1158/2767-9764.CRC-21-0156 |
Ejemplares similares
-
Genomic attributes of homology-directed DNA repair deficiency in metastatic prostate cancer
por: De Sarkar, Navonil, et al.
Publicado: (2021) -
Therapeutic Implications for Intrinsic Phenotype Classification of Metastatic Castration-Resistant Prostate Cancer
por: Coleman, Ilsa M., et al.
Publicado: (2022) -
Reversible epigenetic alterations mediate PSMA expression heterogeneity in advanced metastatic prostate cancer
por: Sayar, Erolcan, et al.
Publicado: (2023) -
Mismatch repair enzyme expression in primary and castrate resistant prostate cancer
por: Nghiem, Belinda, et al.
Publicado: (2016) -
Inter- and intra-tumor heterogeneity of metastatic prostate cancer determined by digital spatial gene expression profiling
por: Brady, Lauren, et al.
Publicado: (2021)