Coexistence of Post-essential Thrombocythemia Myelofibrosis With Monoclonal Gammopathy of Undetermined Significance: A Case Report

Synchronous dual haematological neoplasms are always challenging in both diagnosis and treatment. Here, we report the case of a 73-year-old African American female patient with the coexistence of post-essential thrombocythemia myelofibrosis with MPL positive mutation and monoclonal gammopathy of und...

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Autores principales: Allam, Sarvani Reddy, Naagendran, Mridula Sree, Lawrence Alexander Santhi, Jaison, Khillan, Ratesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635405/
https://www.ncbi.nlm.nih.gov/pubmed/36348874
http://dx.doi.org/10.7759/cureus.29948
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author Allam, Sarvani Reddy
Naagendran, Mridula Sree
Lawrence Alexander Santhi, Jaison
Khillan, Ratesh
author_facet Allam, Sarvani Reddy
Naagendran, Mridula Sree
Lawrence Alexander Santhi, Jaison
Khillan, Ratesh
author_sort Allam, Sarvani Reddy
collection PubMed
description Synchronous dual haematological neoplasms are always challenging in both diagnosis and treatment. Here, we report the case of a 73-year-old African American female patient with the coexistence of post-essential thrombocythemia myelofibrosis with MPL positive mutation and monoclonal gammopathy of undetermined significance (MGUS). Our management plan focuses on her anaemia and regular monitoring for observing MGUS transforming into an aggressive multiple myeloma.
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spelling pubmed-96354052022-11-07 Coexistence of Post-essential Thrombocythemia Myelofibrosis With Monoclonal Gammopathy of Undetermined Significance: A Case Report Allam, Sarvani Reddy Naagendran, Mridula Sree Lawrence Alexander Santhi, Jaison Khillan, Ratesh Cureus Internal Medicine Synchronous dual haematological neoplasms are always challenging in both diagnosis and treatment. Here, we report the case of a 73-year-old African American female patient with the coexistence of post-essential thrombocythemia myelofibrosis with MPL positive mutation and monoclonal gammopathy of undetermined significance (MGUS). Our management plan focuses on her anaemia and regular monitoring for observing MGUS transforming into an aggressive multiple myeloma. Cureus 2022-10-05 /pmc/articles/PMC9635405/ /pubmed/36348874 http://dx.doi.org/10.7759/cureus.29948 Text en Copyright © 2022, Allam et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Allam, Sarvani Reddy
Naagendran, Mridula Sree
Lawrence Alexander Santhi, Jaison
Khillan, Ratesh
Coexistence of Post-essential Thrombocythemia Myelofibrosis With Monoclonal Gammopathy of Undetermined Significance: A Case Report
title Coexistence of Post-essential Thrombocythemia Myelofibrosis With Monoclonal Gammopathy of Undetermined Significance: A Case Report
title_full Coexistence of Post-essential Thrombocythemia Myelofibrosis With Monoclonal Gammopathy of Undetermined Significance: A Case Report
title_fullStr Coexistence of Post-essential Thrombocythemia Myelofibrosis With Monoclonal Gammopathy of Undetermined Significance: A Case Report
title_full_unstemmed Coexistence of Post-essential Thrombocythemia Myelofibrosis With Monoclonal Gammopathy of Undetermined Significance: A Case Report
title_short Coexistence of Post-essential Thrombocythemia Myelofibrosis With Monoclonal Gammopathy of Undetermined Significance: A Case Report
title_sort coexistence of post-essential thrombocythemia myelofibrosis with monoclonal gammopathy of undetermined significance: a case report
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635405/
https://www.ncbi.nlm.nih.gov/pubmed/36348874
http://dx.doi.org/10.7759/cureus.29948
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