Dissection of cellular and molecular mechanisms of aristolochic acid-induced hepatotoxicity via single-cell transcriptomics

BACKGROUND: Aristolochic acids (AAs), a class of carcinogenic and mutagenic natural products from Aristolochia and Asarum plants, are well-known to be responsible for inducing nephrotoxicity and urothelial carcinoma. Recently, accumulating evidence suggests that exposure to AAs could also induce hep...

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Detalles Bibliográficos
Autores principales: Luo, Piao, Chen, Jiayun, Zhang, Qian, Xia, Fei, Wang, Chen, Bai, Yunmeng, Tang, Huan, Liu, Dandan, Gu, Liwei, Du, Qingfeng, Xiao, Wei, Yang, Chuanbin, Wang, Jigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635452/
https://www.ncbi.nlm.nih.gov/pubmed/36349141
http://dx.doi.org/10.1093/pcmedi/pbac023

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