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Analysis of Cyp51 protein sequences shows 4 major Cyp51 gene family groups across fungi

Azole drugs target fungal sterol biosynthesis and are used to treat millions of human fungal infections each year. Resistance to azole drugs has emerged in multiple fungal pathogens including Candida albicans, Cryptococcus neoformans, Histoplasma capsulatum, and Aspergillus fumigatus. The most well-...

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Detalles Bibliográficos
Autores principales: Celia-Sanchez, Brandi N, Mangum, Brandon, Brewer, Marin, Momany, Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635630/
https://www.ncbi.nlm.nih.gov/pubmed/36130263
http://dx.doi.org/10.1093/g3journal/jkac249