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Realgar-induced KRAS mutation lung cancer cell death via KRAS/Raf/MAPK mediates ferroptosis
KRAS is a biomarker for non-small cell lung cancer-targeted therapy, but there is currently no effective KRAS-targeting medication. Realgar is an impelling anti-cancer drug, however its significance in KRAS mutant lung cancer is uncertain. According to our findings, the IC(50) of H23 (KRAS mutant) c...
Autores principales: | Liu, Xiaofeng, Hai, Yang, Dong, Jinqu, Xu, Lan, Hou, Wenqian, Su, Jing, Ren, Weiyu, Liu, Dongling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635866/ https://www.ncbi.nlm.nih.gov/pubmed/36321791 http://dx.doi.org/10.3892/ijo.2022.5447 |
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