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The interpretation of computational model parameters depends on the context

Reinforcement Learning (RL) models have revolutionized the cognitive and brain sciences, promising to explain behavior from simple conditioning to complex problem solving, to shed light on developmental and individual differences, and to anchor cognitive processes in specific brain mechanisms. Howev...

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Detalles Bibliográficos
Autores principales: Eckstein, Maria Katharina, Master, Sarah L, Xia, Liyu, Dahl, Ronald E, Wilbrecht, Linda, Collins, Anne GE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635876/
https://www.ncbi.nlm.nih.gov/pubmed/36331872
http://dx.doi.org/10.7554/eLife.75474
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author Eckstein, Maria Katharina
Master, Sarah L
Xia, Liyu
Dahl, Ronald E
Wilbrecht, Linda
Collins, Anne GE
author_facet Eckstein, Maria Katharina
Master, Sarah L
Xia, Liyu
Dahl, Ronald E
Wilbrecht, Linda
Collins, Anne GE
author_sort Eckstein, Maria Katharina
collection PubMed
description Reinforcement Learning (RL) models have revolutionized the cognitive and brain sciences, promising to explain behavior from simple conditioning to complex problem solving, to shed light on developmental and individual differences, and to anchor cognitive processes in specific brain mechanisms. However, the RL literature increasingly reveals contradictory results, which might cast doubt on these claims. We hypothesized that many contradictions arise from two commonly-held assumptions about computational model parameters that are actually often invalid: That parameters generalize between contexts (e.g. tasks, models) and that they capture interpretable (i.e. unique, distinctive) neurocognitive processes. To test this, we asked 291 participants aged 8–30 years to complete three learning tasks in one experimental session, and fitted RL models to each. We found that some parameters (exploration / decision noise) showed significant generalization: they followed similar developmental trajectories, and were reciprocally predictive between tasks. Still, generalization was significantly below the methodological ceiling. Furthermore, other parameters (learning rates, forgetting) did not show evidence of generalization, and sometimes even opposite developmental trajectories. Interpretability was low for all parameters. We conclude that the systematic study of context factors (e.g. reward stochasticity; task volatility) will be necessary to enhance the generalizability and interpretability of computational cognitive models.
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spelling pubmed-96358762022-11-05 The interpretation of computational model parameters depends on the context Eckstein, Maria Katharina Master, Sarah L Xia, Liyu Dahl, Ronald E Wilbrecht, Linda Collins, Anne GE eLife Computational and Systems Biology Reinforcement Learning (RL) models have revolutionized the cognitive and brain sciences, promising to explain behavior from simple conditioning to complex problem solving, to shed light on developmental and individual differences, and to anchor cognitive processes in specific brain mechanisms. However, the RL literature increasingly reveals contradictory results, which might cast doubt on these claims. We hypothesized that many contradictions arise from two commonly-held assumptions about computational model parameters that are actually often invalid: That parameters generalize between contexts (e.g. tasks, models) and that they capture interpretable (i.e. unique, distinctive) neurocognitive processes. To test this, we asked 291 participants aged 8–30 years to complete three learning tasks in one experimental session, and fitted RL models to each. We found that some parameters (exploration / decision noise) showed significant generalization: they followed similar developmental trajectories, and were reciprocally predictive between tasks. Still, generalization was significantly below the methodological ceiling. Furthermore, other parameters (learning rates, forgetting) did not show evidence of generalization, and sometimes even opposite developmental trajectories. Interpretability was low for all parameters. We conclude that the systematic study of context factors (e.g. reward stochasticity; task volatility) will be necessary to enhance the generalizability and interpretability of computational cognitive models. eLife Sciences Publications, Ltd 2022-11-04 /pmc/articles/PMC9635876/ /pubmed/36331872 http://dx.doi.org/10.7554/eLife.75474 Text en © 2022, Eckstein et al https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Computational and Systems Biology
Eckstein, Maria Katharina
Master, Sarah L
Xia, Liyu
Dahl, Ronald E
Wilbrecht, Linda
Collins, Anne GE
The interpretation of computational model parameters depends on the context
title The interpretation of computational model parameters depends on the context
title_full The interpretation of computational model parameters depends on the context
title_fullStr The interpretation of computational model parameters depends on the context
title_full_unstemmed The interpretation of computational model parameters depends on the context
title_short The interpretation of computational model parameters depends on the context
title_sort interpretation of computational model parameters depends on the context
topic Computational and Systems Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635876/
https://www.ncbi.nlm.nih.gov/pubmed/36331872
http://dx.doi.org/10.7554/eLife.75474
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