Tissue-specific mitochondrial HIGD1C promotes oxygen sensitivity in carotid body chemoreceptors

Mammalian carotid body arterial chemoreceptors function as an early warning system for hypoxia, triggering acute life-saving arousal and cardiorespiratory reflexes. To serve this role, carotid body glomus cells are highly sensitive to decreases in oxygen availability. While the mitochondria and plas...

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Detalles Bibliográficos
Autores principales: Timón-Gómez, Alba, Scharr, Alexandra L, Wong, Nicholas Y, Ni, Erwin, Roy, Arijit, Liu, Min, Chau, Julisia, Lampert, Jack L, Hireed, Homza, Kim, Noah S, Jan, Masood, Gupta, Alexander R, Day, Ryan W, Gardner, James M, Wilson, Richard JA, Barrientos, Antoni, Chang, Andy J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635879/
https://www.ncbi.nlm.nih.gov/pubmed/36255054
http://dx.doi.org/10.7554/eLife.78915

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