Chemiluminescence of lucigenin-tetracycline and its application for sensitive determination of procyanidin

Tetracycline was reported to trigger intense lucigenin chemiluminescence (CL). Based on its significant quenching to lucigenin-tetracycline CL, procyanidin was detected. The mechanism of the lucigenin-tetracycline CL and its quenching by procyanidin were proposed. Under the optimum conditions, the c...

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Detalles Bibliográficos
Autores principales: Quan, Shuai, Ji, Kaixiang, Liu, Fangshuo, Barkae, Tesfaye Hailemariam, Halawa, Mohamed Ibrahim, Hanif, Saima, Lou, Baohua, Li, Jianping, Xu, Guobao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taiwan Food and Drug Administration 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635899/
http://dx.doi.org/10.38212/2224-6614.3411
Descripción
Sumario:Tetracycline was reported to trigger intense lucigenin chemiluminescence (CL). Based on its significant quenching to lucigenin-tetracycline CL, procyanidin was detected. The mechanism of the lucigenin-tetracycline CL and its quenching by procyanidin were proposed. Under the optimum conditions, the calibration curve is linear in the range of 10–1000 nM for procyanidin with a detection limit of 4.4 nM. The RSD for nine replicate determinations of procyanidin was less than 1.7%. Moreover, this method was satisfactorily applied to the determination of procyanidin in human urine samples and health food capsule of grape seed.

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