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Defining the origin, evolution, and immune composition of SDH-deficient renal cell carcinoma
Succinate dehydrogenase (SDH)-deficient renal cell carcinoma represents a rare subtype of hereditary kidney cancer. Clinical diagnosis can be challenging and there is little evidence to guide systemic therapeutic options. We performed genomic profiling of a cohort of tumors through the analysis of w...
Autores principales: | Neves, Joana B., Roberts, Kirsty, Nguyen, Janani Sivakumaran, El Sheikh, Soha, Tran-Dang, My-Anh, Horsfield, Catherine, Mumtaz, Faiz, Campbell, Peter, Stauss, Hans, Tran, Maxine G.B., Mitchell, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636038/ https://www.ncbi.nlm.nih.gov/pubmed/36345344 http://dx.doi.org/10.1016/j.isci.2022.105389 |
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