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Mining the transcriptome of target tissues of autoimmune and degenerative pancreatic β-cell and brain diseases to discover therapies

Target tissues of autoimmune and degenerative diseases show signals of inflammation. We used publicly available RNA-seq data to study whether pancreatic β-cells in type 1 and type 2 diabetes and neuronal tissue in multiple sclerosis and Alzheimer’s disease share inflammatory gene signatures. We obse...

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Detalles Bibliográficos
Autores principales:	Yi, Xiaoyan, Marmontel de Souza, Bianca, Sawatani, Toshiaki, Szymczak, Florian, Marselli, Lorella, Marchetti, Piero, Cnop, Miriam, Eizirik, Decio L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636054/ https://www.ncbi.nlm.nih.gov/pubmed/36345338 http://dx.doi.org/10.1016/j.isci.2022.105376

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