Cargando…

Phenytoin-loaded bioactive nanoparticles for the treatment of diabetic pressure ulcers: formulation and in vitro/in vivo evaluation

Drug repurposing offers the chance to explore the full potential of existing drugs while reducing drug development time and costs. For instance, the anticonvulsant drug phenytoin (PHT) has been investigated for its wound healing properties. However, its poor solubility and variability of doses used...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sheir, Marwa M., Nasra, Maha M. A., Abdallah, Ossama Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636106/ https://www.ncbi.nlm.nih.gov/pubmed/35403947 http://dx.doi.org/10.1007/s13346-022-01156-z

Ejemplares similares

Formulation, in-vitro characterization and clinical evaluation of curcumin in-situ gel for treatment of periodontitis
por: Nasra, Maha M. A., et al.
Publicado: (2017)

Formulation, optimization and characterization of allantoin-loaded chitosan nanoparticles to alleviate ethanol-induced gastric ulcer: in-vitro and in-vivo studies
por: Aman, Reham Mokhtar, et al.
Publicado: (2021)

Formulation and Evaluation of Pravastatin Sodium-Loaded PLGA Nanoparticles: In vitro–in vivo Studies Assessment
por: Elsayed, Seham I, et al.
Publicado: (2023)

Role of Phenytoin in Diabetic Foot Ulcers
por: Bharathi Mohan, Padmalakshmi, et al.
Publicado: (2020)

Formulation and Optimization of Alogliptin-Loaded Polymeric Nanoparticles: In Vitro to In Vivo Assessment
por: Mohanty, Dibyalochan, et al.
Publicado: (2022)

Nose to Brain Delivery of Phenytoin Sodium Loaded Nano Lipid Carriers: Formulation, Drug Release, Permeation and In Vivo Pharmacokinetic Studies
por: Nair, Sreeja C., et al.
Publicado: (2021)

A randomized clinical trial comparing hydrocolloid, phenytoin and simple dressings for the treatment of pressure ulcers [ISRCTN33429693]
por: Hollisaz, Mohammad Taghi, et al.
Publicado: (2004)

Re-Evaluation of the First Phenytoin Paste Healing Effects on Oral Biopsy Ulcers
por: Baharvand, M, et al.
Publicado: (2014)

Formulation and Evaluation of Kaempferol Loaded Nanoparticles against Experimentally Induced Hepatocellular Carcinoma: In Vitro and In Vivo Studies
por: Kazmi, Imran, et al.
Publicado: (2021)

Ocular ketoconazole-loaded proniosomal gels: formulation, ex vivo corneal permeation and in vivo studies
por: Abdelbary, Ghada A., et al.
Publicado: (2017)

Formulation and Evaluation of Prednisolone Sodium Metazoate-Loaded Mucoadhesive Quatsomal Gel for Local Treatment of Recurrent Aphthous Ulcers: Optimization, In Vitro, Ex Vivo, and In Vivo Studies
por: Kassem, Ashraf, et al.
Publicado: (2023)

Hydrocortisone-Loaded Lipid–Polymer Hybrid Nanoparticles for Controlled Topical Delivery: Formulation Design Optimization and In Vitro and In Vivo Appraisal
por: Alsaidan, Omar Awad, et al.
Publicado: (2023)

Novel formulation and evaluation of a Q10-loaded solid lipid nanoparticle cream: in vitro and in vivo studies
por: Farboud, Effat Sadat, et al.
Publicado: (2011)

Formulation, Optimization and Evaluation of Cytarabine-Loaded Iron Oxide Nanoparticles: From In Vitro to In Vivo Evaluation of Anticancer Activity
por: Fule, Ritesh, et al.
Publicado: (2022)

The retinoprotective role of phenytoin
por: Bartollino, Silvia, et al.
Publicado: (2018)

Formulation Development and In Vitro/In Vivo Characterization of Methotrexate-Loaded Nanoemulsion Gel Formulations for Enhanced Topical Delivery
por: Latif, Muhammad Shahid, et al.
Publicado: (2022)

Comparing the Effect of Phenytoin Syrup and Triamcinolone Acetonide Ointment on Aphthous Ulcers in Patients with Behcet’s Syndrome
por: Fani, M M, et al.
Publicado: (2012)

Chondroitin sulfate-functionalized lipid nanoreservoirs: a novel cartilage-targeting approach for intra-articular delivery of cassic acid for osteoarthritis treatment
por: Ebada, Heba M. K., et al.
Publicado: (2022)

Phenytoin inhibits necroptosis
por: von Mässenhausen, Anne, et al.
Publicado: (2018)

Formulation and In vitro Interaction of Rhodamine-B Loaded PLGA Nanoparticles with Cardiac Myocytes
por: Jonderian, Antranik, et al.
Publicado: (2016)

Formulation of Cabotegravir Loaded Gold Nanoparticles: Optimization, Characterization to In-Vitro Cytotoxicity Study
por: Rawat, Purnima, et al.
Publicado: (2022)

Lipid nanoparticles for transdermal delivery of flurbiprofen: formulation, in vitro, ex vivo and in vivo studies
por: Bhaskar, Kesavan, et al.
Publicado: (2009)

DRESSing up to phenytoin
por: Gude, Dilip, et al.
Publicado: (2011)

Variable in Vivo and in Vitro Biological Effects of Cerium Oxide Nanoparticle Formulations
por: Heckman, Karin L., et al.
Publicado: (2020)

Low temperature preparation of diopside nanoparticles: in-vitro bioactivity and drug loading evaluation
por: sobhani, Ava, et al.
Publicado: (2023)

Formulation and optimization of duloxetine hydrochloride buccal films: in vitro and in vivo evaluation
por: El Sharawy, Amr Mostafa, et al.
Publicado: (2017)

A sensitive LC‐MS/MS method for quantification of phenytoin and its major metabolite with application to in vivo investigations of intravenous and intranasal phenytoin delivery
por: Prentice, Richard N., et al.
Publicado: (2022)

Formulation and Evaluation of Transdermal Gel Containing Tacrolimus-Loaded Spanlastics: In Vitro, Ex Vivo and In Vivo Studies
por: Zaki, Randa Mohammed, et al.
Publicado: (2022)

Utilization of Gelling Polymer to Formulate Nanoparticles Loaded with Epalrestat-Cyclodextrin Inclusion Complex: Formulation, Characterization, In-Silico Modelling and In-Vivo Toxicity Evaluation
por: Alvi, Zunaira, et al.
Publicado: (2021)

Formulation, Optimization, In Vitro and In Vivo Evaluation of Saxagliptin-Loaded Lipospheres for an Improved Pharmacokinetic Behavior
por: Rasul, Akhtar, et al.
Publicado: (2021)

Formulation Development of Fast Dissolving Microneedles Loaded with Cubosomes of Febuxostat: In Vitro and In Vivo Evaluation
por: Patel, Brijesh, et al.
Publicado: (2023)

Formulation and in vitro characterization of domperidone loaded solid lipid nanoparticles and nanostructured lipid carriers
por: Thatipamula, RP., et al.
Publicado: (2011)

Preparation of finasteride capsules-loaded drug nanoparticles: formulation, optimization, in vitro, and pharmacokinetic evaluation
por: Ahmed, Tarek A
Publicado: (2016)

Formulation and In-Vitro Characterization of Chitosan-Nanoparticles Loaded with the Iron Chelator Deferoxamine Mesylate (DFO)
por: Lazaridou, Maria, et al.
Publicado: (2020)

5-Fluorouracil-Loaded PLGA Nanoparticles: Formulation, Physicochemical Characterisation, and In VitroAnti-Cancer Activity
por: Gahtani, Reem M., et al.
Publicado: (2023)

Effects of pretreatment with phenobarbitone and phenytoin on the pharmacokinetics and toxicity of phenytoin on the pharmacokinetics and toxicity of misonidazole in mice.
por: Workman, P.
Publicado: (1979)

Phenytoin induced chorea in a pediatric patient: An interaction between phenytoin, phenobarbital and clobazam
por: Barvaliya, Manish, et al.
Publicado: (2011)

Variations in the Blood Phenytoin Levels during Long-Term Combined Treatment with S-1 and Phenytoin
por: Negoro, Yutaka, et al.
Publicado: (2014)

Formulation of Isopropyl Isothiocyanate Loaded Nano Vesicles Delivery Systems: In Vitro Characterization and In Vivo Assessment
por: Kala, Chandra, et al.
Publicado: (2022)

Correction to: Phenytoin inhibits necroptosis
por: von Mässenhausen, Anne, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_9bmg5qr7rlr9jsku1pq140gdsh