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Updated vaccine protects against SARS-CoV-2 variants including Omicron (B.1.1.529) and prevents transmission in hamsters

Current COVID-19 vaccines are based on prototypic spike sequences from ancestral 2019 SARS-CoV-2 strains. However, the ongoing pandemic is fueled by variants of concern (VOC) escaping vaccine-mediated protection. Here we demonstrate how immunization in hamsters using prototypic spike expressed from...

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Detalles Bibliográficos
Autores principales: Sharma, Sapna, Vercruysse, Thomas, Sanchez-Felipe, Lorena, Kerstens, Winnie, Rasulova, Madina, Bervoets, Lindsey, De Keyzer, Carolien, Abdelnabi, Rana, Foo, Caroline S., Lemmens, Viktor, Van Looveren, Dominique, Maes, Piet, Baele, Guy, Weynand, Birgit, Lemey, Philippe, Neyts, Johan, Thibaut, Hendrik Jan, Dallmeier, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636174/
https://www.ncbi.nlm.nih.gov/pubmed/36333374
http://dx.doi.org/10.1038/s41467-022-34439-7

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