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Learning complex dependency structure of gene regulatory networks from high dimensional microarray data with Gaussian Bayesian networks

Reconstruction of Gene Regulatory Networks (GRNs) of gene expression data with Probabilistic Network Models (PNMs) is an open problem. Gene expression datasets consist of thousand of genes with relatively small sample sizes (i.e. are large-p-small-n). Moreover, dependencies of various orders coexist...

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Detalles Bibliográficos
Autores principales: Graafland, Catharina E., Gutiérrez, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636198/
https://www.ncbi.nlm.nih.gov/pubmed/36333425
http://dx.doi.org/10.1038/s41598-022-21957-z

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