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Detection of microsatellite instability high (MSI-H) status by targeted plasma-based genotyping in metastatic breast cancer

We evaluate microsatellite instability-high (MSI-H) status with cell-free DNA (cfDNA) in metastatic breast cancer (MBC) and the association with clinico-genomic characteristics. Patients with MSI-H in cfDNA (Guardant360(®), 74 gene next-generation sequencing (NGS) with MBC are identified. We conduct...

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Detalles Bibliográficos
Autores principales: Vidula, Neelima, Lipman, Andrew, Kato, Shumei, Weipert, Caroline, Hesler, Katherine, Azzi, Georges, Elkhanany, Ahmed, Juric, Dejan, Rodriguez, Estelamari, Faulkner, Colleen, Makhlouf, Paul, Price, Kristin, O’Shaughnessy, Joyce, Bardia, Aditya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636209/
https://www.ncbi.nlm.nih.gov/pubmed/36333333
http://dx.doi.org/10.1038/s41523-022-00490-2