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CdGAP maintains podocyte function and modulates focal adhesions in a Src kinase-dependent manner

Rho GTPases are regulators of the actin cytoskeleton and their activity is modulated by GTPase-activating proteins (GAPs) and guanine nucleotide exchanging factors (GEFs). Glomerular podocytes have numerous actin-based projections called foot processes and their alteration is characteristic of prote...

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Detalles Bibliográficos
Autores principales: Matsuda, Jun, Greenberg, Dina, Ibrahim, Sajida, Maier, Mirela, Aoudjit, Lamine, Chapelle, Jennifer, Baldwin, Cindy, He, Yi, Lamarche-Vane, Nathalie, Takano, Tomoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636259/
https://www.ncbi.nlm.nih.gov/pubmed/36333327
http://dx.doi.org/10.1038/s41598-022-21634-1