Amyloid-associated increases in soluble tau relate to tau aggregation rates and cognitive decline in early Alzheimer’s disease

For optimal design of anti-amyloid-β (Aβ) and anti-tau clinical trials, we need to better understand the pathophysiological cascade of Aβ- and tau-related processes. Therefore, we set out to investigate how Aβ and soluble phosphorylated tau (p-tau) relate to the accumulation of tau aggregates assess...

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Detalles Bibliográficos
Autores principales: Pichet Binette, Alexa, Franzmeier, Nicolai, Spotorno, Nicola, Ewers, Michael, Brendel, Matthias, Biel, Davina, Strandberg, Olof, Janelidze, Shorena, Palmqvist, Sebastian, Mattsson-Carlgren, Niklas, Smith, Ruben, Stomrud, Erik, Ossenkoppele, Rik, Hansson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636262/
https://www.ncbi.nlm.nih.gov/pubmed/36333294
http://dx.doi.org/10.1038/s41467-022-34129-4

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