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Enhanced systemic antilymphoma immune response by photothermal therapy with CpG deoxynucleotide–coated nanoparticles

In preclinical studies, we investigated a novel mechanism of in situ vaccination in lymphoma. Radiation therapy (RT) can induce abscopal responses in lymphoma models, but this has not translated into clinical efficacy. We hypothesized that immune stimulation with cytosine guanine dinucleotide (CpG)...

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Detalles Bibliográficos
Autores principales: Lin, Adam Yuh, Choi, Bongseo, Sim, Taehoon, Yang, Eva, Choi, Hyunjun, Behdad, Amir, Kim, Dong-Hyun, Gordon, Leo I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636326/
https://www.ncbi.nlm.nih.gov/pubmed/35687489
http://dx.doi.org/10.1182/bloodadvances.2022008040