Ablation of sphingosine kinase 2 suppresses fatty liver-associated hepatocellular carcinoma via downregulation of ceramide transfer protein

Hepatocellular carcinoma (HCC) accounts for 90% of primary liver cancer, the third leading cause of cancer-associated death worldwide. With the increasing prevalence of metabolic conditions, non-alcoholic fatty liver disease (NAFLD) is emerging as the fastest-growing HCC risk factor, and it imposes...

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Detalles Bibliográficos
Autores principales: Liu, Xin Tracy, Chung, Long Hoa, Liu, Da, Chen, Jinbiao, Huang, Yu, Teo, Jonathan D., Han, Xingxing Daisy, Zhao, Yinan, Guan, Fiona H. X., Tran, Collin, Lee, Jun Yup, Couttas, Timothy A., Liu, Ken, McCaughan, Geoffery W., Gorrell, Mark D., Don, Anthony S., Zhang, Shubiao, Qi, Yanfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636415/
https://www.ncbi.nlm.nih.gov/pubmed/36333295
http://dx.doi.org/10.1038/s41389-022-00444-0

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