On-microscope staging of live cells reveals changes in the dynamics of transcriptional bursting during differentiation

Determining the mechanisms by which genes are switched on and off during development is a key aim of current biomedical research. Gene transcription has been widely observed to occur in a discontinuous fashion, with short bursts of activity interspersed with periods of inactivity. It is currently no...

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Detalles Bibliográficos
Autores principales: Jeziorska, D. M., Tunnacliffe, E. A. J., Brown, J. M., Ayyub, H., Sloane-Stanley, J., Sharpe, J. A., Lagerholm, B. C., Babbs, C., Smith, A. J. H., Buckle, V. J., Higgs, D. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636426/
https://www.ncbi.nlm.nih.gov/pubmed/36333299
http://dx.doi.org/10.1038/s41467-022-33977-4

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