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Viscoelasticity assessment of tumoral skin with the use of a novel contact-free palpation methodology based upon surface waves

The ensuing pilot investigation sheds new light on characterizing tumoral and non-tumoral human skin mechanical properties that will not only assist the dermatologist’s diagnosis but also could constitute the creation of an Artificial Intelligence database for upcoming research. A modern, non-invasi...

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Autores principales: Bergheau, A., Perrot, J.-L., Vargiolu, R., Zahouani, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636432/
https://www.ncbi.nlm.nih.gov/pubmed/36333449
http://dx.doi.org/10.1038/s41598-022-23483-4
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author Bergheau, A.
Perrot, J.-L.
Vargiolu, R.
Zahouani, H.
author_facet Bergheau, A.
Perrot, J.-L.
Vargiolu, R.
Zahouani, H.
author_sort Bergheau, A.
collection PubMed
description The ensuing pilot investigation sheds new light on characterizing tumoral and non-tumoral human skin mechanical properties that will not only assist the dermatologist’s diagnosis but also could constitute the creation of an Artificial Intelligence database for upcoming research. A modern, non-invasive, and contact-free methodology—UNDERSKIN—was developed, and hinges upon Fourier transform computations that permit the analysis of surface wave dispersion with a specific skin inversion model and viscoelastic model. It yields a detailed look at how particle movements of the medium propagate throughout its near sub-surface, hence a novel knowledge of the mechanical responses of skin tumors. The research results display the tumors’ viscoelastic responses alongside their respective healthy skin outcomes for each skin layer as well as the dermatologist’s touch analysis. Although dermatologists are capable of sensing and having a fair overall assessment of what they are palpating, they are unable heretofore to quantify it and inform where the firmness or softness derives from, which it is necessary to be acquainted with so as to perform an accurate diagnosis, prognosis, treatment, future surgery, and teledermatology.
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spelling pubmed-96364322022-11-06 Viscoelasticity assessment of tumoral skin with the use of a novel contact-free palpation methodology based upon surface waves Bergheau, A. Perrot, J.-L. Vargiolu, R. Zahouani, H. Sci Rep Article The ensuing pilot investigation sheds new light on characterizing tumoral and non-tumoral human skin mechanical properties that will not only assist the dermatologist’s diagnosis but also could constitute the creation of an Artificial Intelligence database for upcoming research. A modern, non-invasive, and contact-free methodology—UNDERSKIN—was developed, and hinges upon Fourier transform computations that permit the analysis of surface wave dispersion with a specific skin inversion model and viscoelastic model. It yields a detailed look at how particle movements of the medium propagate throughout its near sub-surface, hence a novel knowledge of the mechanical responses of skin tumors. The research results display the tumors’ viscoelastic responses alongside their respective healthy skin outcomes for each skin layer as well as the dermatologist’s touch analysis. Although dermatologists are capable of sensing and having a fair overall assessment of what they are palpating, they are unable heretofore to quantify it and inform where the firmness or softness derives from, which it is necessary to be acquainted with so as to perform an accurate diagnosis, prognosis, treatment, future surgery, and teledermatology. Nature Publishing Group UK 2022-11-04 /pmc/articles/PMC9636432/ /pubmed/36333449 http://dx.doi.org/10.1038/s41598-022-23483-4 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Bergheau, A.
Perrot, J.-L.
Vargiolu, R.
Zahouani, H.
Viscoelasticity assessment of tumoral skin with the use of a novel contact-free palpation methodology based upon surface waves
title Viscoelasticity assessment of tumoral skin with the use of a novel contact-free palpation methodology based upon surface waves
title_full Viscoelasticity assessment of tumoral skin with the use of a novel contact-free palpation methodology based upon surface waves
title_fullStr Viscoelasticity assessment of tumoral skin with the use of a novel contact-free palpation methodology based upon surface waves
title_full_unstemmed Viscoelasticity assessment of tumoral skin with the use of a novel contact-free palpation methodology based upon surface waves
title_short Viscoelasticity assessment of tumoral skin with the use of a novel contact-free palpation methodology based upon surface waves
title_sort viscoelasticity assessment of tumoral skin with the use of a novel contact-free palpation methodology based upon surface waves
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636432/
https://www.ncbi.nlm.nih.gov/pubmed/36333449
http://dx.doi.org/10.1038/s41598-022-23483-4
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