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Optic nerve cavitations in glaucoma suspect and glaucoma patients
PURPOSE: Glaucoma is associated with structural changes of the optic nerve head such as deformation, lamina cribosa defects, prelaminar schisis, and peripapillary retinal schisis. We describe optic nerve cavitations that were detected by routine spectral domain optical coherence tomography (OCT). OB...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636442/ https://www.ncbi.nlm.nih.gov/pubmed/36345413 http://dx.doi.org/10.1016/j.ajoc.2022.101733 |
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author | Hong, Bennett Y. Fortune, Brad Kinast, Robert M. Burgoyne, Claude F. Rees, Jack P. Mansberger, Steven L. |
author_facet | Hong, Bennett Y. Fortune, Brad Kinast, Robert M. Burgoyne, Claude F. Rees, Jack P. Mansberger, Steven L. |
author_sort | Hong, Bennett Y. |
collection | PubMed |
description | PURPOSE: Glaucoma is associated with structural changes of the optic nerve head such as deformation, lamina cribosa defects, prelaminar schisis, and peripapillary retinal schisis. We describe optic nerve cavitations that were detected by routine spectral domain optical coherence tomography (OCT). OBSERVATIONS: OCT imaging showed cavitations in 5 eyes of 4 patients with an initial diagnosis of glaucoma or glaucoma suspect. The cavitations were seen as hyporeflective spaces that are sharply delineated from surrounding tissue. They were centered inferonasally, anterior to the lamina cribosa, and at least partially within the Bruch's membrane opening (BMO). They extended from 3 to 6 clock hours. CONCLUSION: AND IMPORTANCE: We describe a new OCT finding in patients with a diagnosis of glaucoma and glaucoma suspect. While previous reports describe cavitations in the choroid in patients with pathological myopia, our patients had minimal refractive error and the cavitations were located within the optic nerve. We will examine these patients over time to determine the impact of this finding on longitudinal changes in structure and function. |
format | Online Article Text |
id | pubmed-9636442 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-96364422022-11-06 Optic nerve cavitations in glaucoma suspect and glaucoma patients Hong, Bennett Y. Fortune, Brad Kinast, Robert M. Burgoyne, Claude F. Rees, Jack P. Mansberger, Steven L. Am J Ophthalmol Case Rep Case Report PURPOSE: Glaucoma is associated with structural changes of the optic nerve head such as deformation, lamina cribosa defects, prelaminar schisis, and peripapillary retinal schisis. We describe optic nerve cavitations that were detected by routine spectral domain optical coherence tomography (OCT). OBSERVATIONS: OCT imaging showed cavitations in 5 eyes of 4 patients with an initial diagnosis of glaucoma or glaucoma suspect. The cavitations were seen as hyporeflective spaces that are sharply delineated from surrounding tissue. They were centered inferonasally, anterior to the lamina cribosa, and at least partially within the Bruch's membrane opening (BMO). They extended from 3 to 6 clock hours. CONCLUSION: AND IMPORTANCE: We describe a new OCT finding in patients with a diagnosis of glaucoma and glaucoma suspect. While previous reports describe cavitations in the choroid in patients with pathological myopia, our patients had minimal refractive error and the cavitations were located within the optic nerve. We will examine these patients over time to determine the impact of this finding on longitudinal changes in structure and function. Elsevier 2022-10-20 /pmc/articles/PMC9636442/ /pubmed/36345413 http://dx.doi.org/10.1016/j.ajoc.2022.101733 Text en © 2022 Published by Elsevier Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Hong, Bennett Y. Fortune, Brad Kinast, Robert M. Burgoyne, Claude F. Rees, Jack P. Mansberger, Steven L. Optic nerve cavitations in glaucoma suspect and glaucoma patients |
title | Optic nerve cavitations in glaucoma suspect and glaucoma patients |
title_full | Optic nerve cavitations in glaucoma suspect and glaucoma patients |
title_fullStr | Optic nerve cavitations in glaucoma suspect and glaucoma patients |
title_full_unstemmed | Optic nerve cavitations in glaucoma suspect and glaucoma patients |
title_short | Optic nerve cavitations in glaucoma suspect and glaucoma patients |
title_sort | optic nerve cavitations in glaucoma suspect and glaucoma patients |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636442/ https://www.ncbi.nlm.nih.gov/pubmed/36345413 http://dx.doi.org/10.1016/j.ajoc.2022.101733 |
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